Protein Alignment l(2)03659 and abcc6

DIOPT Version :10

• Sequence 1: NP_610482.3
• Gene: l(2)03659 / 47905
• FlyBaseID: FBgn0010549
• Length: 1374
• Species: Drosophila melanogaster
• Sequence 2: XP_002932264.3
• Gene: abcc6 / 100493037
• XenbaseID: XB-GENE-6465366
• Length: 1500
• Species: Xenopus tropicalis
• Alignment Length: 1377
• Identity: 452/1377 - (32%)
• Similarity: 722/1377 - (52%)
• Gaps: 158/1377 - (11%)

  Fly    70 TVNSENNSAQNEKEKVLPENPRARSNFISSLCF-WYTIPIFRKGYRKTLDSTDLYRPLEEQKSDI 133
            |.|.:.....|.|::..| .|.:.|:|:|.:.| |:|..:|| ||::.|.:.|::...:...::.
 Frog   188 TFNDDPPFFSNLKKESNP-CPVSESSFLSKVTFSWFTEIMFR-GYKQPLKAEDVWSLRKSDTAEE 250

  Fly   134 LGNRLCASWERE------LKNDGR-SPS-------------------------------LVRALL 160
            :........|:|      ||...| |||                               |::.::
 Frog   251 ILTLFSKGVEKECKKANLLKEPTRFSPSTLDNDMWISQTEKSEIELLLKNQHIQLSQKTLLKVIM 315

  Fly   161 RVFGWQLGFPGLAIFVVELGLRTLQPIF------LVKLISYFSGEPDAAN-AGFYYAVAQIVISA 218
            |.||        ..|::...|.|....|      ||:|:.....:|.|.: .||..||...:...
 Frog   316 RSFG--------LYFLLSALLMTFYTAFLFISPLLVRLLLQLLKDPSAPSWQGFLVAVFLFICPC 372

  Fly   219 LTVMILTPTTFGIHHVCFKMRVAMGSMIFRKALRLTKGALGDTTSGHVVNLISNDIPRLDSAPYT 283
            ...:.|....:..:.:..::|.|:...:::|||.::.....::::|.:|||||.|:.:|......
 Frog   373 CQSLFLHQHDYICYVIGMRLRAAIVGTVYKKALMISSAGRKESSAGEIVNLISTDVQKLMDLATC 437

  Fly   284 VHYLWVGPLQVLVITYLMYQEIGISAVFGVLFMLLFMPIQMYLGTRTSAIQLKAAERTDNRIRMV 348
            |:|:|..|:.::|..|.::|.:||:.:.||...:|.:|...........:|.:..::.|.||:::
 Frog   438 VNYMWSAPVTIIVAMYFLWQTLGIAVLAGVAVFILNLPFMTVFAVIIKRVQEQQMKQKDGRIKII 502

  Fly   349 NEIISAIQVLKMYAWEQPFEQMVTHAREKEMNTIRQGQYIRGFDFARRIV------LSRVAIFLS 407
            :||:..|:|||:||||..|.:.||..|..|:..::.|..:.....|..:.      |:...:||:
 Frog   503 SEILQGIKVLKLYAWENAFMKKVTEFRLMELKAVKTGALLLSGALAVFVASPFWVSLTMFGVFLA 567

  Fly   408 LVGYVILGKVFTPEIAFMITAYYNVLLAAMSIYVPSAIIQTAQFLTSIRRVEQFMQSEELGSSDK 472
            |....||    ..|.||:.....|:|...:.:: |.||...||...|::|:.:|..:|||
 Frog   568 LDEKNIL----DAEKAFVTIILLNILRIPLRMF-PMAITLFAQSSVSLKRMVKFFSAEEL----- 622

  Fly   473 SEGPSKDTVPGNPPSNNNEADLLKSAISIRDLKAKWDPNSPDYTLSGINLEIKPGSVVAVIGLTG 537
                       .|.|.:....|.|.||:||.....|..:.|. .|..||:.|..|::|||:|..|
 Frog   623 -----------EPESVDINDSLSKHAITIRHGTFTWSSSEPP-CLQSINIGIPQGTLVAVVGQVG 675

  Fly   538 SGKSSLIQAILGELKANSGQLQVNGSLSYTSQESWLFSGTVRQNILFGQPMDSQRYEEVVKKCAL 602
            .||:||:.|:|||::...||:.:..|::|..|::|:.:.|.::|:|||:.|:...|::||:.|||
 Frog   676 CGKTSLLSALLGEMEKVEGQVSLMSSVAYVPQQTWIPNATFKENVLFGRKMEKCWYDQVVQACAL 740

  Fly   603 ERDFDLLPLRDNTIVGERGATLSGGQKARISLARSVYRKASIYLLDDPLSAVDASVARHLFDQCV 667
            ..|..:|...:||.:||:|..||||||.|||:||:|||...:||||||||||||.|.:|||:|.:
 Frog   741 LPDLKILSGGENTEIGEKGVNLSGGQKQRISIARAVYRNCDVYLLDDPLSAVDAHVGQHLFEQVI 805

  Fly   668 --RGHLRGSTVVLVTHQEQFLPHVDQIVILANGQIKALGDYESLL-KTG----LITGLGSLSKTD 725
              .|.|:..|.|||||...|||.:|.|:::::|::..:|.|..|| |.|    .:......|...
 Frog   806 GPSGLLKDKTRVLVTHGVSFLPQMDMIIVMSDGRVSEVGTYNELLQKNGAFSEFLNTYARKSVVF 870

  Fly   726 KAKTEEQEPLNLNSP-----------DNKNEVTPIKENSEQTVGGSSSGKEHVERQESGGISLAL 779
            :...|||.|.::...           |..||...:....|...|..:.....:    :|.:.|::
 Frog   871 EESYEEQTPNSIQGAMKMKGKHSARNDTDNETDDVANEIEADAGKLTEADVAL----TGRVKLSV 931

  Fly   780 YRKYFQAGGGLVAFLVMLSS--SVLAQVAVTGGDYFLTYWVKKESTAAGHGEMEDMESKSMDVYK 842
            |.:|.:..|   .:.:::|:  .::.|.|....:|::..|......   :|..:. .|..:.||.
 Frog   932 YLEYCKIMG---KWYLLISALFFIVQQAASLSYNYWIGLWADDPPV---NGTQQH-TSLRLGVYS 989

  Fly   843 YTLIIILSVIMNLSSSFLLFNIAKKASIRLHNTIFNRVTRADMHFFSINKHGSILNRFTKDMSQV 907
            :..::....|...||:.::..::  .|.:||:.:...:.|..:.||.....|::.|||.|:|..:
 Frog   990 FLGVMQALSIFAASSTIIVGGVS--VSRQLHSRLLYSILRCPLSFFERTPSGNLTNRFAKEMDII 1052

  Fly   908 DEVLPVVLVDVMQIALWLAGIIIVIANVNPLLLVPTLMLSVIFYHLRNLYLKTSRDLKRVEAINR 972
            |..:|.||:..:.:.|.:|.|::||:...||..|..:.|.::::.|:..|:.:||.|||::|:::
 Frog  1053 DNTVPQVLMLFIIMMLTIAEILLVISIATPLAAVAFIPLGLLYFFLQRFYVASSRQLKRLDAVSK 1117

  Fly   973 SPVYSHLAASLNGLTTIRALDAQRVLEKEFDSYQDAHSSAFFMYISTSQAFGYC---------MN 1028
            ||:|:|...||.|:..|||...|    :.|  .||.:     |.::.:|.|.:|         :.
 Frog  1118 SPLYTHFNESLQGVYVIRAFREQ----ERF--IQDNN-----MRLNMNQRFYFCSFVANRWLSVR 1171

  Fly  1029 C-----ICVIYISIITLSF-FAFPPGNGADVGLVITQAMGLIDMVQWGVRQTAELENTMTAVERV 1087
            |     ..|..::|:.:.| ....||.   |||.:..::.|..:::..|....::|....:||||
 Frog  1172 CDFLSNFIVFTVAIVGVLFRDNITPGL---VGLAVVNSLRLTGVLKEAVHVATDMETNSVSVERV 1233

  Fly  1088 VEYESIEPEGMLEAP---DDKKPPKTWPEQGEIIFKELNLRYTPNAKAENVLKSLSFVIQPREKV 1149
            .||...||    |||   |:......||.:|:|.|:...|||.|:  .:..||:::..||..|||
 Frog  1234 KEYCDAEP----EAPWTSDNASDLSNWPSKGKIEFQNYGLRYRPD--LDLALKNVTASIQQGEKV 1292

  Fly  1150 GIVGRTGAGKSSLINALFR-LSYTDGSVLIDTRDTRQMGLHDLRRQISIIPQEPVLFSGTMRYNL 1213
            |||||||||||||...||| |....|.:.||.:|..::|||:||.:|:||||:|||||||:|.||
 Frog  1293 GIVGRTGAGKSSLTLGLFRILEPATGRICIDEKDISELGLHELRSKITIIPQDPVLFSGTLRMNL 1357

  Fly  1214 DPFDEYSDEKLWGCLEEVKLKEVVSDLPDGLASKISEGGTNFSVGQRQLVCLARAILRENRILVM 1278
            ||||.|||..:|..|:...||...|.||:||:...:|||.|.|||||||||||||:||:.:|||:
 Frog  1358 DPFDNYSDNDIWVALQLAHLKVFASGLPEGLSYICTEGGENLSVGQRQLVCLARALLRKTKILVL 1422

  Fly  1279 DEATANVDPQTDGLIQATIRSKFRDCTVLTIAHRLHTIIDSDKVMVMDAGRVVEFGSPYELMTKS 1343
            |||||.||.:||.|||.|||.:|.|||::||||||:||:|..:|:|.|.|.:|||.:|..|:  .
 Frog  1423 DEATAAVDLETDDLIQNTIRKEFEDCTIITIAHRLNTIMDYTRVVVFDKGEIVEFDTPATLL--E 1485

  Fly  1344 DSKVFHNLVNQS 1355
            :..:|:::...:
 Frog  1486 NKGLFYSMARDA 1497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(2)03659	NP_610482.3	PLN03130	83..1369	CDD:215595	448/1364 (33%)
abcc6	XP_002932264.3	MRP_assoc_pro	5..1499	CDD:188098	452/1377 (33%)