DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment betaTry and Prss36

DIOPT Version :9

Sequence 1:	NP_001286314.1	Gene:	betaTry / 47901	FlyBaseID:	FBgn0010357	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	XP_017167884.1	Gene:	Prss36 / 77613	MGIID:	1924863	Length:	863	Species:	Mus musculus

Alignment Length:	246	Identity:	80/246 - (32%)
Similarity:	128/246 - (52%)	Gaps:	21/246 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 PQLDGRIVGGTATTISSFPWQISLQRSGSHSCGGSIYSARVIVTAAHCLQS----VSASSLQIRA 85
            |:...|||||:.....::|||:||.:.|.|.||||:.:...:::||||..:    ..|..|.:..
Mouse    42 PEPSSRIVGGSDAHPGTWPWQVSLHQGGGHICGGSLIAPSWVLSAAHCFVTNGTLEPADELSVLL 106

  Fly    86 GSSYWS---SGGVVAKVSSFKNHEGYNANTMVNDIAVLHLSSSLSFSSTIKAIGL--ASSNPANG 145
            |.....   .|..:..|::....:.|:...:..|:|:|.|:|......:::.:.|  ||...|:|
Mouse   107 GVHSQDGPLEGAHMRSVATILIPDNYSTVELGADLALLRLASPAKLGPSVRPVCLPRASHLFAHG 171

  Fly   146 AAASVSGWG-TESSGSSSIPSQLRYVNVNIVSQSRCSS--SSYGYGN---QIKSSMICA-FASG- 202
            .|...:||| .:.:....:|..|:.|.:.::.::.|..  |..|..|   |:...|:|| :.:|
Mouse   172 TACWATGWGDVQEAVPLPLPWVLQEVELRLLGEAACQCLYSRPGPFNLTFQLLPGMLCAGYPAGR 236

  Fly   203 KDSCQGDSGGPLV--SGG--VLVGVVSWGYGCAAANYPGVYADVAALRSWV 249
            :|:||||||||||  .||  .|.|:.|:|:||...|.|||:..||...||:
Mouse   237 RDTCQGDSGGPLVCEDGGRWFLAGITSFGFGCGRRNRPGVFTAVAPYESWI 287

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
betaTry	NP_001286314.1	Tryp_SPc	30..249	CDD:214473	78/239 (33%)
betaTry	NP_001286314.1	Tryp_SPc	31..252	CDD:238113	78/240 (33%)
Prss36	XP_017167884.1	Tryp_SPc	48..290	CDD:238113	78/240 (33%)
		Tryp_SPc	331..532	CDD:389826
		Tryp_SPc	607..789	CDD:389826
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167839471
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24276
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.030