Protein Alignment betaTry and TPSB2

DIOPT Version :10

• Sequence 1: NP_524904.1
• Gene: betaTry / 47901
• FlyBaseID: FBgn0010357
• Length: 253
• Species: Drosophila melanogaster
• Sequence 2: NP_077078.5
• Gene: TPSB2 / 64499
• HGNCID: 14120
• Length: 275
• Species: Homo sapiens
• Alignment Length: 271
• Identity: 92/271 - (33%)
• Similarity: 130/271 - (47%)
• Gaps: 26/271 - (9%)

  Fly     1 MLKFLILLSAVACALGGTIP-EGLLPQLDGRIVGGTATTISSFPWQISLQ---RSGSHSCGGSIY 61
            ||..|:|...|..:.....| .|...|..| ||||.....|.:|||:||:   |...|.||||:.
Human     1 MLNLLLLALPVLASRAYAAPAPGQALQRVG-IVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSLI 64

  Fly    62 SARVIVTAAHC----LQSVSASSLQIRAGSSYWSSGGVVAKVSSFKNHEGYNANTMVNDIAVLHL 122
            ..:.::|||||    ::.::|..:|:|....|:..  .:..||....|..:....:..|||:|.|
Human    65 HPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQD--QLLPVSRIIVHPQFYTAQIGADIALLEL 127

  Fly   123 SSSLSFSSTIKAIGL--ASSNPANGAAASVSGWG-TESSGSSSIPSQLRYVNVNIVSQSRCSSSS 184
            ...::.||.:..:.|  ||.....|....|:||| .::......|..|:.|.|.|:....| .:.
Human   128 EEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHIC-DAK 191

  Fly   185 YGYG-------NQIKSSMICAFASGKDSCQGDSGGPL---VSGGVL-VGVVSWGYGCAAANYPGV 238
            |..|       ..::..|:||..:.:|||||||||||   |:|..| .||||||.|||..|.||:
Human   192 YHLGAYTGDDVRIVRDDMLCAGNTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGI 256

  Fly   239 YADVAALRSWV 249
            |..|.....|:
Human   257 YTRVTYYLDWI 267

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
betaTry	NP_524904.1	Tryp_SPc	30..249	CDD:214473	82/239 (34%)
TPSB2	NP_077078.5	Tryp_SPc	31..268	CDD:238113	83/240 (35%)