DRSC/TRiP Functional Genomics Resources

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Protein Alignment betaTry and PRSS22

DIOPT Version :9

Sequence 1:NP_001286314.1 Gene:betaTry / 47901 FlyBaseID:FBgn0010357 Length:253 Species:Drosophila melanogaster
Sequence 2:NP_071402.1 Gene:PRSS22 / 64063 HGNCID:14368 Length:317 Species:Homo sapiens


Alignment Length:273 Identity:99/273 - (36%)
Similarity:139/273 - (50%) Gaps:36/273 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly     5 LILLSAVACALGGTIPEGLL---PQLDGRIVGGTATTISSFPWQISLQRSGSHSCGGSIYSARVI 66
            |:||::.|......||....   ||...|:|||..:|.|.:||.:|:|::|:|.|.||:.::|.:
Human    21 LLLLASTAILNAARIPVPPACGKPQQLNRVVGGEDSTDSEWPWIVSIQKNGTHHCAGSLLTSRWV 85

  Fly    67 VTAAHC---------LQSVSASSLQIRAGSSYWSSGGVV----AKVSSFKNHEGYNANTMVNDIA 118
            :|||||         |.||...:.|:....|.....||.    ..|.|:|  ||..|     |||
Human    86 ITAAHCFKDNLNKPYLFSVLLGAWQLGNPGSRSQKVGVAWVEPHPVYSWK--EGACA-----DIA 143

  Fly   119 VLHLSSSLSFSSTIKAIGLASSN---PANGAAASVSGWGTESSG-SSSIPSQLRYVNVNIVSQSR 179
            ::.|..|:.||..:..|.|..::   |.| ....:||||:...| ....|..|:.:.|.|:....
Human   144 LVRLERSIQFSERVLPICLPDASIHLPPN-THCWISGWGSIQDGVPLPHPQTLQKLKVPIIDSEV 207

  Fly   180 CSSSSYGYGNQ--IKSSMICA-FASG-KDSCQGDSGGPL---VSGG-VLVGVVSWGYGCAAANYP 236
            ||...:....|  |...|:|| :..| :|:|.|||||||   |.|. :|.|::|||.|||..|.|
Human   208 CSHLYWRGAGQGPITEDMLCAGYLEGERDACLGDSGGPLMCQVDGAWLLAGIISWGEGCAERNRP 272

  Fly   237 GVYADVAALRSWV 249
            |||..::|.||||
Human   273 GVYISLSAHRSWV 285

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
betaTryNP_001286314.1 Tryp_SPc 30..249 CDD:214473 89/243 (37%)
Tryp_SPc 31..252 CDD:238113 90/244 (37%)
PRSS22NP_071402.1 Tryp_SPc 50..288 CDD:238113 90/244 (37%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 157 1.000 Inparanoid score I4288
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.960

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