Protein Alignment betaTry and PRSS2

DIOPT Version :9

• Sequence 1: NP_001286314.1
• Gene: betaTry / 47901
• FlyBaseID: FBgn0010357
• Length: 253
• Species: Drosophila melanogaster
• Sequence 2: NP_001290343.1
• Gene: PRSS2 / 5645
• HGNCID: 9483
• Length: 261
• Species: Homo sapiens
• Alignment Length: 270
• Identity: 97/270 - (35%)
• Similarity: 143/270 - (52%)
• Gaps: 39/270 - (14%)

  Fly     2 LKFLILLSAVACALGGTIPEGLLPQLDGRIVGGTATTISSFPWQISLQRSGSHSCGGSIYSARVI 66
            :..|::|:.||.|:.....:      |.:||||.....:|.|:|:|| .||.|.||||:.|.:.:
Human     1 MNLLLILTFVAAAVAAPFDD------DDKIVGGYICEENSVPYQVSL-NSGYHFCGGSLISEQWV 58

  Fly    67 VTAAHCLQSVSASSL----------QIRAG----------SSYWSSGGVVAKVSSFKNHEGYNAN 111
            |:|.||.:|...|.|          |:|.|          ..:.::..::       .|..||:.
Human    59 VSAGHCYKSAINSKLSGRGCEYHRIQVRLGEHNIEVLEGNEQFINAAKII-------RHPKYNSR 116

  Fly   112 TMVNDIAVLHLSSSLSFSSTIKAIGLASSNPANGAAASVSGWGTESSGSSSIPSQLRYVNVNIVS 176
            |:.|||.::.|||....:|.:.||.|.::.||.|..:.:||||...|..:..|.:|:.::..::|
Human   117 TLDNDILLIKLSSPAVINSRVSAISLPTAPPAAGTESLISGWGNTLSSGADYPDELQCLDAPVLS 181

  Fly   177 QSRCSSSSYGYGNQIKSSMICA--FASGKDSCQGDSGGPLVSGGVLVGVVSWGYGCAAANYPGVY 239
            |:.|.:|   |..:|.::|.|.  ...||||||||||||:||.|.|.|:||||||||..|.||||
Human   182 QAECEAS---YPGKITNNMFCVGFLEGGKDSCQGDSGGPVVSNGELQGIVSWGYGCAQKNRPGVY 243

  Fly   240 ADVAALRSWV 249
            ..|.....|:
Human   244 TKVYNYVDWI 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
betaTry	NP_001286314.1	Tryp_SPc	30..249	CDD:214473	90/240 (38%)
		Tryp_SPc	31..252	CDD:238113	91/241 (38%)
PRSS2	NP_001290343.1	Tryp_SPc	23..253	CDD:214473	90/240 (38%)
		Tryp_SPc	24..256	CDD:238113	91/241 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D469244at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X21
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.920