Protein Alignment betaTry and KLK15

DIOPT Version :10

• Sequence 1: NP_524904.1
• Gene: betaTry / 47901
• FlyBaseID: FBgn0010357
• Length: 253
• Species: Drosophila melanogaster
• Sequence 2: NP_059979.2
• Gene: KLK15 / 55554
• HGNCID: 20453
• Length: 256
• Species: Homo sapiens
• Alignment Length: 263
• Identity: 86/263 - (32%)
• Similarity: 126/263 - (47%)
• Gaps: 36/263 - (13%)

  Fly     7 LLSAVACALGGTIPEGLLPQLDG-RIVGGTATTISSFPWQISLQRSGSHSCGGSIYSARVIVTAA 70
            ||..::..|..|..:      || :::.|......|.|||::|...|..:||.|:.|...:::||
Human     3 LLLTLSFLLASTAAQ------DGDKLLEGDECAPHSQPWQVALYERGRFNCGASLISPHWVLSAA 61

  Fly    71 HCLQS------VSASSLQIRAGSSYWSSGGVVAKVSSFKNHEGYNANTMVNDIAVLHLSSSLSFS 129
            || ||      :...:|:.|.|...      :...|....|..|.|.:..|||.:|.|......:
Human    62 HC-QSRFMRVRLGEHNLRKRDGPEQ------LRTTSRVIPHPRYEARSHRNDIMLLRLVQPARLN 119

  Fly   130 STIKAIGLASSNPANGAAASVSGWGTES------SGSS----SIPSQLRYVNVNIVSQSRCSSSS 184
            ..::...|.:..|..|.|..|||||..|      :||.    |:|..|...|::|:|.:.|..|
Human   120 PQVRPAVLPTRCPHPGEACVVSGWGLVSHNEPGTAGSPRSQVSLPDTLHCANISIISDTSCDKS- 183

  Fly   185 YGYGNQIKSSMICAFASGK--DSCQGDSGGPLVSGGVLVGVVSWG-YGCAAANYPGVYADVAALR 246
              |..::.::|:||.|.|:  :||:||||||||.||:|.|:|||| ..|.....||||..|....
Human   184 --YPGRLTNTMVCAGAEGRGAESCEGDSGGPLVCGGILQGIVSWGDVPCDNTTKPGVYTKVCHYL 246

  Fly   247 SWV 249
            .|:
Human   247 EWI 249

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
betaTry	NP_524904.1	Tryp_SPc	30..249	CDD:214473	79/237 (33%)
KLK15	NP_059979.2	Tryp_SPc	25..249	CDD:214473	79/233 (34%)