DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment betaTry and Prss53

DIOPT Version :9

Sequence 1:	NP_001286314.1	Gene:	betaTry / 47901	FlyBaseID:	FBgn0010357	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	XP_006230384.1	Gene:	Prss53 / 499270	RGDID:	1566127	Length:	591	Species:	Rattus norvegicus

Alignment Length:	321	Identity:	78/321 - (24%)
Similarity:	128/321 - (39%)	Gaps:	98/321 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 LILLSAV-----------ACALGGTIPEGLLPQLDGRIVGGTATTISSFPWQISLQRSGSHSCGG 58
            |:::.||           ||...|..|..  || :|..:.|      .:|||.|::|.|.|.|.|
  Rat     9 LLIVGAVIVIEGLQAAQRACGQRGPGPPE--PQ-EGNTLPG------EWPWQASVRRQGVHICSG 64

  Fly    59 SIYSARVIVTAAHCLQSVSASSLQIRAGSSYW------------SSGGVVAKVSSFKNHEGYNAN 111
            |:.:...::|||||.:.::.:.|      |.|            |.|.....|::.:..:.||..
  Rat    65 SLVADTWVLTAAHCFEKMATAEL------SSWSVVLGSLKQEGLSPGAEEVGVAALQLPKAYNHY 123

  Fly   112 TMVNDIAVLHLSSSLSFSSTIKAIGLASSNPAN----GAAASVSGWGTESSGSSSIP------SQ 166
            :..:|:|:|.|:..:..::      |....|.:    ||:...:||...:|.....|      ||
  Rat   124 SQGSDLALLQLTHPIVHTT------LCLPQPTHHFPFGASCWATGWDQNTSDGKYCPRHKSRESQ 182

  Fly   167 ------------------------------LRYVNVNIVSQSRCSSSSYG------YGNQIKSSM 195
                                          ||.:.:.::|:..| :..|.      ..|..:|.|
  Rat   183 TGSVLTVLALCSHCVSELDSTLSPLPVSRTLRNLRLRLISRPTC-NCLYNRLHQRLLANPARSGM 246

  Fly   196 ICAFASG--KDSCQGDSGGPLV-----SGGVLVGVVSWGYGCAAANYPGVYADVAALRSWV 249
            :|..|..  :..||||||||::     ...|.||::|:...||..:.|.:..|:||..||:
  Rat   247 LCGGAQPGVQGPCQGDSGGPVMCREPDGHWVQVGIISFTSNCAQEDTPVLLTDMAAHSSWL 307

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
betaTry	NP_001286314.1	Tryp_SPc	30..249	CDD:214473	67/283 (24%)
betaTry	NP_001286314.1	Tryp_SPc	31..252	CDD:238113	68/284 (24%)
Prss53	XP_006230384.1	Tryp_SPc	45..310	CDD:238113	68/282 (24%)
Prss53	XP_006230384.1	Tryp_SPc	341..561	CDD:238113
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166343318
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24276
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.030