DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment betaTry and epsilonTry

DIOPT Version :9

Sequence 1:	NP_001286314.1	Gene:	betaTry / 47901	FlyBaseID:	FBgn0010357	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	NP_525112.1	Gene:	epsilonTry / 49080	FlyBaseID:	FBgn0010425	Length:	256	Species:	Drosophila melanogaster

Alignment Length:	253	Identity:	159/253 - (62%)
Similarity:	191/253 - (75%)	Gaps:	0/253 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MLKFLILLSAVACALGGTIPEGLLPQLDGRIVGGTATTISSFPWQISLQRSGSHSCGGSIYSARV 65
            ||||.:|||.:||||.||||:|||||||||||||..|:|.:.|:|:||||.|||.|||||||..:
  Fly     1 MLKFAVLLSVLACALAGTIPDGLLPQLDGRIVGGYETSIDAHPYQVSLQRYGSHFCGGSIYSHDI 65

  Fly    66 IVTAAHCLQSVSASSLQIRAGSSYWSSGGVVAKVSSFKNHEGYNANTMVNDIAVLHLSSSLSFSS 130
            ::||||||||:.|..|:||.||:||.|||.|..|.||:||||||:.|||||||::.:.|.|||.|
  Fly    66 VITAAHCLQSIEAKDLKIRVGSTYWRSGGSVHSVRSFRNHEGYNSRTMVNDIAIIRIESDLSFRS 130

  Fly   131 TIKAIGLASSNPANGAAASVSGWGTESSGSSSIPSQLRYVNVNIVSQSRCSSSSYGYGNQIKSSM 195
            :|:.|.:|.|||..||.|.||||||..||.|:||..|..|::.|:..|||.|..:|||.:||.:|
  Fly   131 SIREIRIADSNPREGATAVVSGWGTTESGGSTIPDHLLAVDLEIIDVSRCRSDEFGYGKKIKDTM 195

  Fly   196 ICAFASGKDSCQGDSGGPLVSGGVLVGVVSWGYGCAAANYPGVYADVAALRSWVINNA 253
            :||:|..||:||||||||||||..|||||||||||....|||||||||....|:...|
  Fly   196 LCAYAPHKDACQGDSGGPLVSGDRLVGVVSWGYGCGDVRYPGVYADVAHFHEWIERTA 253

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
betaTry	NP_001286314.1	Tryp_SPc	30..249	CDD:214473	134/218 (61%)
betaTry	NP_001286314.1	Tryp_SPc	31..252	CDD:238113	134/220 (61%)
epsilonTry	NP_525112.1	Tryp_SPc	30..249	CDD:214473	134/218 (61%)
epsilonTry	NP_525112.1	Tryp_SPc	31..252	CDD:238113	134/220 (61%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45452454
Domainoid	1	1.000	156	1.000	Domainoid score	I4174
eggNOG	1	0.900	-	-		E33208_3BBP0
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	181	1.000	Inparanoid score	I3969
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG25816
OrthoDB	1	1.010	-	-		D109274at50557
OrthoFinder	1	1.000	-	-		FOG0000678
OrthoInspector	1	1.000	-	-		mtm8948
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24276
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X21
	11	10.910