DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment betaTry and zgc:92590

DIOPT Version :9

Sequence 1:	NP_001286314.1	Gene:	betaTry / 47901	FlyBaseID:	FBgn0010357	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	NP_001007055.1	Gene:	zgc:92590 / 474322	ZFINID:	ZDB-GENE-041024-15	Length:	247	Species:	Danio rerio

Alignment Length:	255	Identity:	90/255 - (35%)
Similarity:	135/255 - (52%)	Gaps:	23/255 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MLKFLILLSAVACALGGTIPEGLLPQLDGRIVGGTATTISSFPWQISL-QRSGSHSCGGSIYSAR 64
            |:.|.:|:.||||:            .|.:|:||...:.:|.||||.| ..:|...||.|:.:.|
Zfish     3 MIVFALLVLAVACS------------ADDKIIGGYECSPNSQPWQIYLTYDNGQRWCGASLINDR 55

  Fly    65 VIVTAAHCLQSVSASSLQIRAGS-SYWSSGGVVAKVSSFK--NHEGYNANTMVNDIAVLHLSSSL 126
            ..|:||||.  :.|:.|.:..|. :.....|...::.:.|  .|..||..|:.||..::.|....
Zfish    56 WAVSAAHCY--LVANRLTVHLGEHNVAVEEGTEQRIKAEKVIPHPKYNDYTLDNDFMLIKLKEPA 118

  Fly   127 SFSSTIKAIGLASSNPANGAAASVSGWGTESSGSSSIPSQLRYVNVNIVSQSRCSSSSYGYGNQI 191
            .|:..::.:.|.:|..:.|....|||||...:.....|..|:.:|:.::::::|..:   ||.||
Zfish   119 VFNQYVQPVPLTTSCSSEGEQCLVSGWGNLINTGVVYPDVLQCLNLPVLTRAQCEGA---YGWQI 180

  Fly   192 KSSMICA--FASGKDSCQGDSGGPLVSGGVLVGVVSWGYGCAAANYPGVYADVAALRSWV 249
            ..:|.||  ...|||:||||||||::..|.|.||||||||||.:.|||||.:|.....||
Zfish   181 TKNMFCAGFMEGGKDACQGDSGGPVICNGELRGVVSWGYGCADSGYPGVYTEVCRYTDWV 240

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
betaTry	NP_001286314.1	Tryp_SPc	30..249	CDD:214473	80/224 (36%)
betaTry	NP_001286314.1	Tryp_SPc	31..252	CDD:238113	82/225 (36%)
zgc:92590	NP_001007055.1	Tryp_SPc	20..240	CDD:214473	80/224 (36%)
zgc:92590	NP_001007055.1	Tryp_SPc	21..243	CDD:238113	82/225 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BBP0
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	181	1.000	Inparanoid score	I3969
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D469244at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X21
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.870