DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment betaTry and Tmprss11c

DIOPT Version :9

Sequence 1:	NP_001286314.1	Gene:	betaTry / 47901	FlyBaseID:	FBgn0010357	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	NP_001003979.1	Gene:	Tmprss11c / 408213	RGDID:	1302967	Length:	418	Species:	Rattus norvegicus

Alignment Length:	238	Identity:	89/238 - (37%)
Similarity:	125/238 - (52%)	Gaps:	29/238 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 RIVGGTATTISSFPWQISLQRSGSHSCGGSIYSARVIVTAAHC-LQSVSASSLQIRAGSSYWSSG 93
            ::.||.......:|||.|||::..|.||.::.|...::||||| ::|.:....::       |.|
  Rat   186 KVAGGQDAEEGEWPWQASLQQNNVHRCGATLISNSWLITAAHCFVRSANPKDWKV-------SFG 243

  Fly    94 GVVAK------VSSFKNHEGYNANTMVNDIAVLHLSSSLSFSSTIKAIGLASSN---PANGAAAS 149
            .:::|      |.|...||.|:.....|||||:.|||.:.:.:.|:...|..:.   |.|....
  Rat   244 FLLSKPQAQRAVKSIVIHENYSYPAHNNDIAVVRLSSPVLYENNIRRACLPEATQKFPPNSDVV- 307

  Fly   150 VSGWGT-ESSGSSSIPSQLRYVNVNIVSQSRCSSSSYGYGNQIKSSMICA-FASGK-DSCQGDSG 211
            |:|||| :|.|.|  |:.|:...|.|:....|:|.. .||..|...|:|| |..|: |:||||||
  Rat   308 VTGWGTLKSDGDS--PNILQKGRVKIIDNKTCNSGK-AYGGVITPGMLCAGFLEGRVDACQGDSG 369

  Fly   212 GPLV---SGGV--LVGVVSWGYGCAAANYPGVYADVAALRSWV 249
            ||||   |.|:  |.|:||||..||..|.||||..|...|.|:
  Rat   370 GPLVSEDSKGIWFLAGIVSWGDECALPNKPGVYTRVTHYRDWI 412

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
betaTry	NP_001286314.1	Tryp_SPc	30..249	CDD:214473	88/236 (37%)
betaTry	NP_001286314.1	Tryp_SPc	31..252	CDD:238113	89/237 (38%)
Tmprss11c	NP_001003979.1	SEA	62..157	CDD:279699
		Tryp_SPc	186..412	CDD:214473	88/236 (37%)
		Tryp_SPc	187..415	CDD:238113	89/237 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D469244at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X21
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.920