DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment betaTry and ovch1

DIOPT Version :9

Sequence 1:	NP_001286314.1	Gene:	betaTry / 47901	FlyBaseID:	FBgn0010357	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	NP_956439.2	Gene:	ovch1 / 393114	ZFINID:	ZDB-GENE-040426-834	Length:	556	Species:	Danio rerio

Alignment Length:	265	Identity:	90/265 - (33%)
Similarity:	134/265 - (50%)	Gaps:	41/265 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 VACALGGTIPEGLLPQLDGRIVGGTATTISSFPWQISLQRSGSHSCGGSIYSARVIVTAAHCLQS 75
            |...:...:||..:.  :.||:||......|:|||:|||.:...:|||:|.....::||.||.:.
Zfish    39 VLAGIRSFVPEDEVE--ESRIIGGKEAWAHSWPWQVSLQYNDVPTCGGAILDQLWVITAGHCFKR 101

  Fly    76 VSASSLQIRAGSSYWSSGGVVA---------------KVSSFKNHEGYNANTMVNDIAVLHLSSS 125
            ....|:        |::  ||.               :|....:|:.||..|..||||:|.|.|.
Zfish   102 YKKPSM--------WNA--VVGLHNLDNANESSRESIQVQKIFSHKNYNQKTNENDIALLKLQSP 156

  Fly   126 LSFSSTIKAIGLASSNPANGAAASVSGWG--TESSGSSSIPSQLRYVNVNIVSQSRCSSSSYGYG 188
            |.||..::.||:.:::.......:|:|||  ||:...:   |:|:.|||.:....:|:..   |.
Zfish   157 LVFSKFVRPIGVFNNDLPPLVTCTVTGWGSVTENGPQA---SRLQEVNVTVYEPQKCNRF---YR 215

  Fly   189 NQIKSSMICAFAS--GKDSCQGDSGGPL--VSGG--VLVGVVSWGYGCAAANYPGVYADVAALRS 247
            .::..|||||.|:  |.|:|||||||||  ..|.  .|.||||||.||..|..||||..:...|.
Zfish   216 GKVLKSMICAGANEGGMDACQGDSGGPLSCFDGERYKLAGVVSWGVGCGRAQKPGVYTTLYHYRQ 280

  Fly   248 WVINN 252
            |::::
Zfish   281 WMVSS 285

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
betaTry	NP_001286314.1	Tryp_SPc	30..249	CDD:214473	86/241 (36%)
betaTry	NP_001286314.1	Tryp_SPc	31..252	CDD:238113	86/243 (35%)
ovch1	NP_956439.2	Tryp_SPc	56..281	CDD:214473	86/240 (36%)
		Tryp_SPc	57..281	CDD:238113	85/239 (36%)
		Tryp_SPc	331..551	CDD:238113
		Tryp_SPc	331..549	CDD:214473
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910