DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment betaTry and tmprss4b

DIOPT Version :9

Sequence 1:	NP_001286314.1	Gene:	betaTry / 47901	FlyBaseID:	FBgn0010357	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	NP_001119849.1	Gene:	tmprss4b / 327651	ZFINID:	ZDB-GENE-030131-5862	Length:	432	Species:	Danio rerio

Alignment Length:	249	Identity:	93/249 - (37%)
Similarity:	132/249 - (53%)	Gaps:	20/249 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 AVACALGGTIPEGLLPQLDGRIVGGTATTISSFPWQISLQRSGSHSCGGSIYSARVIVTAAHCL- 73
            :|:|:..|.:..      :.|||||..|:|..:|||:|||.:..|.||||:.|...|::||||.
Zfish   187 SVSCSDCGEVVG------EDRIVGGVETSIEHWPWQVSLQFNHRHMCGGSLLSTSWIISAAHCFT 245

  Fly    74 ---QSVSASSLQIRAGSSYWSSGGVVAKVSSFKNHEGYNANTMVNDIAVLHLSSSLSFSSTIKAI 135
               |.:|..:: :...:......||  .|.....|:.||..|...|||:|.|:..:....:|..:
Zfish   246 GRTQELSRWTV-VLGQTKVMDVVGV--SVDMIVIHKDYNRLTNDFDIAMLKLTWPVKTGESILPV 307

  Fly   136 GLASSNPANGAAASVSGWGTESSGSSSIPSQLRYVNVNIVSQSRCSSSSYGYGNQIKSSMICA-F 199
            .|.....|......|:|||....| .::|:.|:..:|.:|::|.||..:. |.:.|...|:|| |
Zfish   308 CLPPHQLAIKDMLVVTGWGLLKEG-GALPTVLQKASVPLVNRSECSKPTI-YSSSITPRMLCAGF 370

  Fly   200 ASGK-DSCQGDSGGPLV---SGGVLVGVVSWGYGCAAANYPGVYADVAALRSWV 249
            ..|. |:||||||||||   |...|:|:||||.|||....|||||||..|..|:
Zfish   371 LQGNVDACQGDSGGPLVYLSSRWQLIGIVSWGVGCAREGKPGVYADVTQLLDWI 424

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
betaTry	NP_001286314.1	Tryp_SPc	30..249	CDD:214473	89/227 (39%)
betaTry	NP_001286314.1	Tryp_SPc	31..252	CDD:238113	89/228 (39%)
tmprss4b	NP_001119849.1	SRCR_2	100..179	CDD:292133
		SRCR	105..>175	CDD:278931
		Tryp_SPc	201..424	CDD:214473	89/227 (39%)
		Tryp_SPc	202..427	CDD:238113	89/228 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910