Protein Alignment betaTry and CFD

DIOPT Version :10

• Sequence 1: NP_524904.1
• Gene: betaTry / 47901
• FlyBaseID: FBgn0010357
• Length: 253
• Species: Drosophila melanogaster
• Sequence 2: NP_001304264.1
• Gene: CFD / 1675
• HGNCID: 2771
• Length: 260
• Species: Homo sapiens
• Alignment Length: 261
• Identity: 78/261 - (29%)
• Similarity: 132/261 - (50%)
• Gaps: 25/261 - (9%)

  Fly     2 LKFLILLSAVAC---ALGGTIPEGLLPQLDGRIVGGTATTISSFPWQISLQRSGSHSCGGSIYSA 63
            |..|:||.|.||   |.....|    |:  |||:||......:.|:..|:|.:|:|.|||.:.:.
Human     7 LAVLVLLGAAACGEEAWAWAAP----PR--GRILGGREAEAHARPYMASVQLNGAHLCGGVLVAE 65

  Fly    64 RVIVTAAHCLQSVSASSLQIRAGSSYWSSG-------GVVAKVSSFKNHEGYNANTMVNDIAVLH 121
            :.:::|||||:..:...:|:..|:...|..       .|:..|.    |.....:|:.:|:.:|.
Human    66 QWVLSAAHCLEDAADGKVQVLLGAHSLSQPEPSKRLYDVLRAVP----HPDSQPDTIDHDLLLLQ 126

  Fly   122 LSSSLSFSSTIKAI--GLASSNPANGAAASVSGWGTESSGSSSIPSQLRYVNVNIVSQSRCSSSS 184
            ||...:....::.:  .....:.|.|....|:|||..:..... |..|::|.:.::.::.|:..:
Human   127 LSEKATLGPAVRPLPWQRVDRDVAPGTLCDVAGWGIVNHAGRR-PDSLQHVLLPVLDRATCNRRT 190

  Fly   185 YGYGNQIKSSMICAFASGKDSCQGDSGGPLVSGGVLVGVVSWGYG-CAAANYPGVYADVAALRSW 248
            : :...|...::||.::.:|||:||||||||.||||.|||:.|.. |.....||:|..||:..:|
Human   191 H-HDGAITERLMCAESNRRDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTRVASYAAW 254

  Fly   249 V 249
            :
Human   255 I 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
betaTry	NP_524904.1	Tryp_SPc	30..249	CDD:214473	66/228 (29%)
CFD	NP_001304264.1	Tryp_SPc	33..258	CDD:238113	66/229 (29%)