DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment betaTry and PRSS36

DIOPT Version :10

Sequence 1:NP_524904.1 Gene:betaTry / 47901 FlyBaseID:FBgn0010357 Length:253 Species:Drosophila melanogaster
Sequence 2:NP_775773.2 Gene:PRSS36 / 146547 HGNCID:26906 Length:855 Species:Homo sapiens


Alignment Length:259 Identity:82/259 - (31%)
Similarity:128/259 - (49%) Gaps:34/259 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly    20 PEGL---LPQLDGRIVGGTATTISSFPWQISLQRSGSHSCGGSIYSARVIVTAAHCLQSVSASSL 81
            ||.|   .|:...|||||:.....::|||:||...|.|.||||:.:...:::||||.  ::..:|
Human    33 PEDLDCGRPEPSARIVGGSNAQPGTWPWQVSLHHGGGHICGGSLIAPSWVLSAAHCF--MTNGTL 95

  Fly    82 QIRAGSSYWS------------SGGVVAKVSSFKNHEGYNANTMVNDIAVLHLSSSLSFSSTIKA 134
            :   .::.||            .|.....|::......|:...:..|:|:|.|:|..|....:..
Human    96 E---PAAEWSVLLGVHSQDGPLDGAHTRAVAAIVVPANYSQVELGADLALLRLASPASLGPAVWP 157

  Fly   135 IGL--ASSNPANGAAASVSGWG-TESSGSSSIPSQLRYVNVNIVSQSRCSS--SSYGYGN---QI 191
            :.|  ||....:|.|...:||| .:.:....:|..|:.|.:.::.::.|..  |..|..|   ||
Human   158 VCLPRASHRFVHGTACWATGWGDVQEADPLPLPWVLQEVELRLLGEATCQCLYSQPGPFNLTLQI 222

  Fly   192 KSSMICA-FASG-KDSCQGDSGGPLV--SGG--VLVGVVSWGYGCAAANYPGVYADVAALRSWV 249
            ...|:|| :..| :|:||||||||||  .||  ...|:.|:|:||...|.|||:..||...:|:
Human   223 LPGMLCAGYPEGRRDTCQGDSGGPLVCEEGGRWFQAGITSFGFGCGRRNRPGVFTAVATYEAWI 286

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
betaTryNP_524904.1 Tryp_SPc 30..249 CDD:214473 77/244 (32%)
PRSS36NP_775773.2 Tryp_SPc 47..289 CDD:238113 77/245 (31%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 292..316
Tryp_SPc 330..538 CDD:473915
Tryp_SPc 601..783 CDD:473915
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.