Protein Alignment betaTry and Cfd

DIOPT Version :10

• Sequence 1: NP_524904.1
• Gene: betaTry / 47901
• FlyBaseID: FBgn0010357
• Length: 253
• Species: Drosophila melanogaster
• Sequence 2: NP_038487.1
• Gene: Cfd / 11537
• MGIID: 87931
• Length: 259
• Species: Mus musculus
• Alignment Length: 254
• Identity: 75/254 - (29%)
• Similarity: 130/254 - (51%)
• Gaps: 19/254 - (7%)

  Fly     5 LILLSAVACALGGTIPEGLLPQLDGRIVGGTATTISSFPWQISLQRSGSHSCGGSIYSARVIVTA 69
            |::|.|..||          .|..|||:||......:.|:..|:|.:|:|.|||::...:.:::|
Mouse    10 LVILGAAVCA----------AQPRGRILGGQEAAAHARPYMASVQVNGTHVCGGTLLDEQWVLSA 64

  Fly    70 AHCLQSVS-ASSLQIRAGSSYWSSGGVVAK---VSSFKNHEGYNANTMVNDIAVLHLSSSLSFSS 130
            |||:..|: ..|:|:..|:...|:.....:   |.|...|.|...:::.:|:.:..||.:.|...
Mouse    65 AHCMDGVTDDDSVQVLLGAHSLSAPEPYKRWYDVQSVVPHPGSRPDSLEDDLILFKLSQNASLGP 129

  Fly   131 TIKAIGL--ASSNPANGAAASVSGWGTESSGSSSIPSQLRYVNVNIVSQSRCSSSSYGYGNQIKS 193
            .::.:.|  .......|....|:|||..:..... |..|..:.|:|::::.|:..:| :...:..
Mouse   130 HVRPLPLQYEDKEVEPGTLCDVAGWGVVTHAGRR-PDVLHQLRVSIMNRTTCNLRTY-HDGVVTI 192

  Fly   194 SMICAFASGKDSCQGDSGGPLVSGGVLVGVVSWGYG-CAAANYPGVYADVAALRSWVIN 251
            :|:||.::.:|:|:||||.|||.|..:.|||:||.. |.....||||..|::.|.|:.|
Mouse   193 NMMCAESNRRDTCRGDSGSPLVCGDAVEGVVTWGSRVCGNGKKPGVYTRVSSYRMWIEN 251

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
betaTry	NP_524904.1	Tryp_SPc	30..249	CDD:214473	66/225 (29%)
Cfd	NP_038487.1	Tryp_SPc	26..252	CDD:238113	67/228 (29%)
		Self-inhibitor loop. /evidence=ECO:0000250|UniProtKB:P00746	224..228		2/3 (67%)