DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Nmdmc and EMB3127

DIOPT Version :9

Sequence 1:	NP_476929.1	Gene:	Nmdmc / 47895	FlyBaseID:	FBgn0010222	Length:	309	Species:	Drosophila melanogaster
Sequence 2:	NP_191971.1	Gene:	EMB3127 / 825824	AraportID:	AT4G00620	Length:	360	Species:	Arabidopsis thaliana

Alignment Length:	298	Identity:	136/298 - (45%)
Similarity:	194/298 - (65%)	Gaps:	15/298 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 AQIIDGKAIAQEVRTQLAHELKGMEAAGYPKPHLTAVIVGEDPASEKYVANKMVACREVGISSET 72
            |.:|||||:|:::|.::..|:..|:.:....|.|..::||:...|..||.||..||..|||.|..
plant    69 AIVIDGKAVAKKIRDEITIEVSRMKESIGVIPGLAVILVGDRKDSATYVRNKKKACDSVGIKSFE 133

  Fly    73 KRLPASTTQEELLQLIADLNKDPQVTGILVQLPVPEHINERTICNAVDVDKDVDGFNEVNIGRTA 137
            .||...:::||:|:.::..|.||.|.|||||||:|.|::|:.|.|||.::||||||:.:||||.|
plant   134 VRLAEDSSEEEVLKSVSGFNDDPSVHGILVQLPLPSHMDEQNILNAVSIEKDVDGFHPLNIGRLA 198

  Fly   138 LDMEAN--IPATPLGVKRLLEHMKIETLGRNAVVVGRSKNVSLPMAILLHADGKYATKAMDATVT 200
            :.....  :|.||.|...||....||..|:.|||:|||..|.:|.|:||..:        ||||:
plant   199 MRGREPLFVPCTPKGCIELLHRYNIEIKGKRAVVIGRSNIVGMPAALLLQRE--------DATVS 255

  Fly   201 ICHRYTP-PKELARHCRQADIIVVAVGKPGLITKDMVKPGACVIDVGINRIKDESTGQ-FKLVGD 263
            |.|..|. |:|:.   |:||||:.|||:|.::....:||||.:||||||.::|.|..: ::||||
plant   256 IIHSRTKNPEEIT---READIIISAVGQPNMVRGSWIKPGAVLIDVGINPVEDPSAARGYRLVGD 317

  Fly   264 VDFEEVRQVAGHITPVPGGVGPMTVAMLMHNTLKAARK 301
            :.:||..:||..||||||||||||:|||:.|||.:|::
plant   318 ICYEEASKVASAITPVPGGVGPMTIAMLLSNTLTSAKR 355

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nmdmc	NP_476929.1	FolD	9..304	CDD:223268	135/297 (45%)
		THF_DHG_CYH	10..126	CDD:279147	49/115 (43%)
		THF_DHG_CYH_C	129..303	CDD:280955	82/177 (46%)
EMB3127	NP_191971.1	PLN02616	1..360	CDD:215332	136/298 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	108	1.000	Domainoid score	I2149
eggNOG	1	0.900	-	-		E1_COG0190
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	248	1.000	Inparanoid score	I1035
OMA	1	1.010	-	-		QHG61254
OrthoDB	1	1.010	-	-		D1004679at2759
OrthoFinder	1	1.000	-	-		FOG0001810
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100216
Panther	1	1.100	-	-	LDO	PTHR48099
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1169
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.840