Protein Alignment Nmdmc and mthfd2l

DIOPT Version :9

• Sequence 1: NP_476929.1
• Gene: Nmdmc / 47895
• FlyBaseID: FBgn0010222
• Length: 309
• Species: Drosophila melanogaster
• Sequence 2: XP_005167203.1
• Gene: mthfd2l / 327496
• ZFINID: ZDB-GENE-030131-5707
• Length: 348
• Species: Danio rerio
• Alignment Length: 295
• Identity: 151/295 - (51%)
• Similarity: 207/295 - (70%)
• Gaps: 0/295 - (0%)

  Fly     6 NMAQIIDGKAIAQEVRTQLAHELKGMEAAGYPKPHLTAVIVGEDPASEKYVANKMVACREVGISS 70
            ::|.::.|..:|:::..::..::..:.|.|..:|||:.::||:|.||..||.||......:|:||
Zfish    49 HVATVVSGAELARQIHKEVQSDIAKLVAEGNRRPHLSVILVGDDHASHTYVRNKTRTASLLGMSS 113

  Fly    71 ETKRLPASTTQEELLQLIADLNKDPQVTGILVQLPVPEHINERTICNAVDVDKDVDGFNEVNIGR 135
            .|...|:|.:|||:|:||...|:|..::|:|||||:|||||||.|||||..:||||||:.||||:
Zfish   114 STIFRPSSVSQEEMLELIDKFNRDRNISGLLVQLPLPEHINERAICNAVAPEKDVDGFHIVNIGK 178

  Fly   136 TALDMEANIPATPLGVKRLLEHMKIETLGRNAVVVGRSKNVSLPMAILLHADGKYATKAMDATVT 200
            ..||....||||...|..::....:||:|:|.:||||||||.:|:|:|||:|.|:.....||||.
Zfish   179 LCLDQRCMIPATAAAVWEIIRRTGLETVGKNVLVVGRSKNVGMPIAMLLHSDRKHERSGGDATVI 243

  Fly   201 ICHRYTPPKELARHCRQADIIVVAVGKPGLITKDMVKPGACVIDVGINRIKDESTGQFKLVGDVD 265
            :.||.||...|....|.|||::.|.|.|.|||.||||.||.||||||||::|..||:.:||||||
Zfish   244 MAHRCTPLPRLKELARLADIVIAAAGVPHLITADMVKEGAAVIDVGINRMQDPVTGKSRLVGDVD 308

  Fly   266 FEEVRQVAGHITPVPGGVGPMTVAMLMHNTLKAAR 300
            ||.|::.||.||||||||||||:||:|.||:.||:
Zfish   309 FEAVKEKAGFITPVPGGVGPMTIAMVMKNTVTAAK 343

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nmdmc	NP_476929.1	FolD	9..304	CDD:223268	150/292 (51%)
		THF_DHG_CYH	10..126	CDD:279147	50/115 (43%)
		THF_DHG_CYH_C	129..303	CDD:280955	96/172 (56%)
mthfd2l	XP_005167203.1	PRK14190	50..343	CDD:184560	150/292 (51%)
		THF_DHG_CYH	53..169	CDD:279147	50/115 (43%)
		NAD_bind_m-THF_DH_Cyclohyd	164..343	CDD:133448	101/178 (57%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592533
Domainoid	1	1.000	209	1.000	Domainoid score	I2789
eggNOG	1	0.900	-	-		E1_COG0190
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	330	1.000	Inparanoid score	I2431
OMA	1	1.010	-	-		QHG61254
OrthoDB	1	1.010	-	-		D1004679at2759
OrthoFinder	1	1.000	-	-		FOG0001810
OrthoInspector	1	1.000	-	-		otm26407
orthoMCL	1	0.900	-	-		OOG6_100216
Panther	1	1.100	-	-	LDO	PTHR48099
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1169
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	14	13.770