Protein Alignment Nmdmc and dao-3

DIOPT Version :9

• Sequence 1: NP_476929.1
• Gene: Nmdmc / 47895
• FlyBaseID: FBgn0010222
• Length: 309
• Species: Drosophila melanogaster
• Sequence 2: NP_509362.1
• Gene: dao-3 / 181065
• WormBaseID: WBGene00000929
• Length: 303
• Species: Caenorhabditis elegans
• Alignment Length: 318
• Identity: 119/318 - (37%)
• Similarity: 176/318 - (55%)
• Gaps: 38/318 - (11%)

  Fly     7 MAQIIDGKAIAQEVRTQLAHELKGMEAA----GYPKPH--LTAVIVGEDPASEKYVANKMVACRE 65
            :|:|:.|...:::|    .|:: |.:.|    .:|..|  |..|.||....|..|:.:|:...:|
 Worm     2 VAEIVSGLEYSKKV----LHDV-GQKIAKTREHHPNFHAVLAIVQVGNRSDSNVYINSKLKKAKE 61

  Fly    66 VGISSETKRLPASTTQEELLQLIADLNKDPQVTGILVQLPV--PEHINERTICNAVDVDKDVDGF 128
            :|...:..:||.:.||.:|.:.|..||.|.::.||::|||:  ...|:..::.:.:|..|||||.
 Worm    62 IGADGKLIKLPDTITQGDLKREIMALNHDNEIDGIIIQLPLDCKHEIDADSVIDLIDPLKDVDGL 126

  Fly   129 NEVNIGRTAL-DMEANI-PATPLGVKRLLEHMKIE---TLGRNAVVVGRSKNVSLPMAILL--HA 186
            ..:|.||.|. :::..| |.||.|...|::....:   ..|:..||:||||.|..|.|.|.  |
 Worm   127 TRINAGRLARGELQRTIFPCTPFGCLYLVQQATGDANFVSGKEVVVLGRSKIVGSPAAALFLWH- 190

  Fly   187 DGKYATKAMDATVTICHRYTPPKELARHCRQADIIVVAVGKPGLITKDMVKPGACVIDVGINRIK 251
                     ..||||||..||  .|...|.:|||::||:|:...:..|.:||||.|||.||| :.
 Worm   191 ---------HGTVTICHSKTP--NLKEKCLRADILIVAIGRKHFVKADWIKPGAFVIDCGIN-VG 243

  Fly   252 DESTGQFKLVGDVDFEEVRQVAGHITPVPGGVGPMTVAMLMHNTLKAARK----QFDD 305
            |:...: |:.||||.|..::|||.:|||||||||||||||:.||.:.|::    |.||
 Worm   244 DDPNSR-KIYGDVDTEAAKEVAGFLTPVPGGVGPMTVAMLIRNTFEQAKRRRLGQKDD 300

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nmdmc	NP_476929.1	FolD	9..304	CDD:223268	116/313 (37%)
		THF_DHG_CYH	10..126	CDD:279147	35/123 (28%)
		THF_DHG_CYH_C	129..303	CDD:280955	77/184 (42%)
dao-3	NP_509362.1	FolD	5..294	CDD:223268	115/307 (37%)
		THF_DHG_CYH	5..124	CDD:279147	35/123 (28%)
		NAD_bind_m-THF_DH_Cyclohyd	119..291	CDD:133448	81/185 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	172	1.000	Inparanoid score	I2740
Isobase	1	0.950	-	0	Normalized mean entropy	S1545
OMA	1	1.010	-	-		QHG61254
OrthoDB	1	1.010	-	-		D1004679at2759
OrthoFinder	1	1.000	-	-		FOG0001810
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100216
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4671
SonicParanoid	1	1.000	-	-		X1169
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	12	11.820