Protein Alignment Nmdmc and mthfd2

DIOPT Version :9

• Sequence 1: NP_476929.1
• Gene: Nmdmc / 47895
• FlyBaseID: FBgn0010222
• Length: 309
• Species: Drosophila melanogaster
• Sequence 2: NP_001123716.1
• Gene: mthfd2 / 100170462
• XenbaseID: XB-GENE-941965
• Length: 335
• Species: Xenopus tropicalis
• Alignment Length: 296
• Identity: 173/296 - (58%)
• Similarity: 218/296 - (73%)
• Gaps: 0/296 - (0%)

  Fly     6 NMAQIIDGKAIAQEVRTQLAHELKGMEAAGYPKPHLTAVIVGEDPASEKYVANKMVACREVGISS 70
            |.|.:|.|:.:|:::|.:..||::...|||..:|||:.|:||::|||..||.||..|..:|||||
 Frog    28 NEAVVISGRKLARQIRQEARHEVEQWVAAGNKRPHLSVVLVGDNPASHSYVLNKTKAAADVGISS 92

  Fly    71 ETKRLPASTTQEELLQLIADLNKDPQVTGILVQLPVPEHINERTICNAVDVDKDVDGFNEVNIGR 135
            ||...|.|.|:||||.||..||.|..|.|:|||||:|||::||.|||||..|||||||:.||:||
 Frog    93 ETILKPTSITEEELLDLINKLNNDDHVDGLLVQLPLPEHLDERAICNAVTPDKDVDGFHVVNVGR 157

  Fly   136 TALDMEANIPATPLGVKRLLEHMKIETLGRNAVVVGRSKNVSLPMAILLHADGKYATKAMDATVT 200
            ..||..:.:||||.||..:::...|.|||:|.||.||||||.:|:|:|||.||::.....|||||
 Frog   158 MCLDQYSMLPATPWGVWEIIKRTGIPTLGKNVVVAGRSKNVGMPIAMLLHTDGRHERPGGDATVT 222

  Fly   201 ICHRYTPPKELARHCRQADIIVVAVGKPGLITKDMVKPGACVIDVGINRIKDESTGQFKLVGDVD 265
            |.|||||.::|..|.:.|||:|.|.|.|.|||.||:|.||.||||||||::|..||:.|||||||
 Frog   223 ISHRYTPKEQLKMHTKIADIVVAAAGIPNLITADMIKEGAAVIDVGINRVQDPVTGKPKLVGDVD 287

  Fly   266 FEEVRQVAGHITPVPGGVGPMTVAMLMHNTLKAARK 301
            ||.||:.|.:|||||||||||||||||.||:.||:|
 Frog   288 FEGVRKKASYITPVPGGVGPMTVAMLMKNTIIAAKK 323

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nmdmc	NP_476929.1	FolD	9..304	CDD:223268	171/293 (58%)
		THF_DHG_CYH	10..126	CDD:279147	62/115 (54%)
		THF_DHG_CYH_C	129..303	CDD:280955	105/173 (61%)
mthfd2	NP_001123716.1	FolD	32..326	CDD:223268	171/292 (59%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	211	1.000	Domainoid score	I2747
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H21321
Inparanoid	1	1.050	344	1.000	Inparanoid score	I2270
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1004679at2759
OrthoFinder	1	1.000	-	-		FOG0001810
OrthoInspector	1	1.000	-	-		otm48943
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4671
SonicParanoid	1	1.000	-	-		X1169
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.090