DRSC/TRiP Functional Genomics Resources

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Protein Alignment hbn and ISX

DIOPT Version :9

Sequence 1:NP_788420.1 Gene:hbn / 47894 FlyBaseID:FBgn0008636 Length:409 Species:Drosophila melanogaster
Sequence 2:NP_001290437.1 Gene:ISX / 91464 HGNCID:28084 Length:245 Species:Homo sapiens


Alignment Length:189 Identity:67/189 - (35%)
Similarity:80/189 - (42%) Gaps:64/189 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly   145 SDMERPRK---------VRRSRTTFTTFQLHQLERAFEKTQYPDVFTREDLAMRLDLSEARVQVW 200
            |.:|:|.|         .||.||||||.|||:||:.|..|.||||..|..||.|::|.|||||:|
Human    65 SGLEKPPKDQPQEGRKSKRRVRTTFTTEQLHELEKIFHFTHYPDVHIRSQLAARINLPEARVQIW 129

  Fly   201 FQNRRAKWRKREKFMNQDKAGYLLPEQGLPEFPLGIP------------------LPPHG----- 242
            |||:||||||      |:|.|.|...|.|.|..:.:|                  .||..     
Human   130 FQNQRAKWRK------QEKIGNLGAPQQLSEASVALPTNLDVAGPTWTSTALRRLAPPTSCCPSA 188

  Fly   243 ---------------LPGHPGSMQSEFWPPHFALHQHFNPAAAAAAGLLPQHLMAPHYK 286
                           ||.||...|.   .|...:||...|...    :||    .||.|
Human   189 QDQLASAWFPAWITLLPAHPWETQP---VPGLPIHQTCIPVLC----ILP----PPHPK 236

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
hbnNP_788420.1 Homeobox 156..209 CDD:278475 34/52 (65%)
ISXNP_001290437.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 38..86 6/20 (30%)
Homeobox 86..138 CDD:278475 34/51 (67%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000011
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24329
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
33.010

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