Protein Alignment hbn and RHOXF2B

DIOPT Version :9

• Sequence 1: NP_788420.1
• Gene: hbn / 47894
• FlyBaseID: FBgn0008636
• Length: 409
• Species: Drosophila melanogaster
• Sequence 2: NP_001093155.1
• Gene: RHOXF2B / 727940
• HGNCID: 33519
• Length: 288
• Species: Homo sapiens
• Alignment Length: 267
• Identity: 62/267 - (23%)
• Similarity: 94/267 - (35%)
• Gaps: 106/267 - (39%)

  Fly    66 GHPHHIHHLH---SSNSNGSNHLSHQQQQQHSQQQHHSQQQQQQQQLQVQAKREDSPTNTDGGLD 127
            |.|.|:...:   :|.|:|:...|.|.:::..||.                   ..|....|||:
Human    84 GVPGHLWEGNLEGTSGSDGNVEDSDQSEKEPGQQY-------------------SRPQGAVGGLE 129

  Fly   128 VDNDDELSSSLNNGHDLSDMERPRKVRRSRTTFTTFQLHQLERAFEKTQYPDVFTREDLAMRLDL 192
            ..|..:     .|.|                .||..||.:||..|::.|:|..|.|..||..:::
Human   130 PGNAQQ-----PNVH----------------AFTPLQLQELECIFQREQFPSEFLRRRLARSMNV 173

  Fly   193 SEARVQVWFQNRRAKWRKREKFMNQDKAGYLLPEQG----------------------------- 228
            :|..||:||:|||||||:.::.:   .|..:||...
Human   174 TELAVQIWFENRRAKWRRHQRAL---MARNMLPFMAVGQPVMVTAAEAITAPLFISGMRDDYFWD 235

  Fly   229 ----------LPEF-PLGIPLPPHGLPGHPGSMQSEFWPPHFALHQHFNPAAAAAAGLLPQHLMA 282
                      :|.| |..:|||...||..|.:.|:||.|..|                    ::.
Human   236 HSHSSSLCFPMPPFPPPSLPLPLMLLPPMPPAGQAEFGPFPF--------------------VIV 280

  Fly   283 PHYKLPN 289
            |.:..||
Human   281 PSFTFPN 287

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hbn	NP_788420.1	Homeobox	156..209	CDD:278475	23/52 (44%)
RHOXF2B	NP_001093155.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	16..136		15/75 (20%)
		Homeobox	140..190	CDD:278475	23/49 (47%)
		Nuclear localization signal. /evidence=ECO:0000250	186..195		5/8 (63%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910