Protein Alignment hbn and pitx2

DIOPT Version :10

• Sequence 1: NP_788420.1
• Gene: hbn / 47894
• FlyBaseID: FBgn0008636
• Length: 409
• Species: Drosophila melanogaster
• Sequence 2: NP_001017227.1
• Gene: pitx2 / 549981
• XenbaseID: XB-GENE-482492
• Length: 345
• Species: Xenopus tropicalis
• Alignment Length: 324
• Identity: 100/324 - (30%)
• Similarity: 149/324 - (45%)
• Gaps: 61/324 - (18%)

  Fly    68 PHHIHHL------HSSNSNGSNHLSHQQQQQHSQQQHHSQQQQQQQQL---------------QV 111
            |.|:.||      .:|:.:..:|..|||.|.|.||.||.|.||.|.|.               :.
 Frog     7 PLHLDHLVGSKLATASSHHQHHHQQHQQHQHHHQQHHHQQHQQPQPQAVTLVSMASSLGQRSGEC 71

  Fly   112 QAKREDSPTNTDGGLDVDNDDELSSSLNNGHDLSDMERPRKVRRSRTTFTTFQLHQLERAFEKTQ 176
            :|:.|....:.....:..:.|:...|.|......|..:.::.||.||.||:.||.:||..|::.:
 Frog    72 KARLEVHTISDTSSPEAADKDKSHQSKNEDSSTDDPSKKKRQRRQRTHFTSQQLQELEATFQRNR 136

  Fly   177 YPDVFTREDLAMRLDLSEARVQVWFQNRRAKWRKREKFMNQDKAGYLLPEQGL-PEFPLGIPLPP 240
            |||:.|||::|:..:|:||||:|||:||||||||||:  ||...   |.:.|. |:|
 Frog   137 YPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRER--NQQAE---LCKNGFGPQF-------- 188

  Fly   241 HGLPGHPGSMQSEFWPPHFALHQHFNPAAAAAAGLLPQHLMA---PHYKLPNFHTLLSQYMGLSN 302
                  .|.||     |:..::..::....||.||....|..   |.:...|.:.|.||.| .|:
 Frog   189 ------NGLMQ-----PYDDMYPSYSYNNWAAKGLTSASLSTKSFPFFNSMNVNPLSSQSM-FSS 241

  Fly   303 LNGI----FGAGAAAAAAAASAGYPQNLSLHAGLSAMSQVSPPCSNSS-PRESPKLVPHPTPPH 361
            .|.|    ..:|...:|.....|...|     .|:.::.:|.|..|:: |..:....| ||||:
 Frog   242 PNSISSMSMSSGMVPSAVTGVPGSGLN-----SLNNLNNLSNPSLNTAVPTSACPYAP-PTPPY 299

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hbn	NP_788420.1	Homeodomain	154..210	CDD:459649	32/55 (58%)
pitx2	NP_001017227.1	Homeodomain	114..170	CDD:459649	32/55 (58%)
		OAR	303..320	CDD:461067