Protein Alignment hbn and DPRX

DIOPT Version :10

• Sequence 1: NP_788420.1
• Gene: hbn / 47894
• FlyBaseID: FBgn0008636
• Length: 409
• Species: Drosophila melanogaster
• Sequence 2: NP_001012746.1
• Gene: DPRX / 503834
• HGNCID: 32166
• Length: 191
• Species: Homo sapiens
• Alignment Length: 228
• Identity: 58/228 - (25%)
• Similarity: 91/228 - (39%)
• Gaps: 54/228 - (23%)

  Fly   135 SSSLNNGHDLSDMERPRKVRRSRTTFTTFQLHQLERAFEKTQYPDVFTREDLAMRLDLSEARVQV 199
            |..|..|.|  .|...||    ||.||..||..|...|.:..||:...::::|.::|:....:||
Human     4 SEDLRKGKD--QMHSHRK----RTMFTKKQLEDLNILFNENPYPNPSLQKEMASKIDIHPTVLQV 62

  Fly   200 WFQNRRAKWRKREKFMNQDKAGYLLPEQGLPEFPLGIPLPPHGLPGHPGSMQSEFWPPHFALHQH 264
            ||:|.|||.:|.       |..::..:|..|: |   |:|..|:....|...::..|.
Human    63 WFKNHRAKLKKA-------KCKHIHQKQETPQ-P---PIPEGGVSTSVGLRNADTLPR------- 109

  Fly   265 FNPAAAAAAGLLPQHLMAPHYKL---PNFHTLLSQYMGL----------SNLNGIFGAGAAAAAA 316
             .|.||...||:......|.::|   ||.....:.::|.          .|:..::....:...|
Human   110 -LPNAAHPIGLVYTGHRVPSFQLILYPNLKVPANDFIGHRIVHFGCCRDPNIYCLYPILESQVCA 173

  Fly   317 AASAGYPQNLSLHAGLSAMSQVSPPCSNSSPRE 349
            .         |.|:|       ||.||::..||
Human   174 P---------SFHSG-------SPACSSNQSRE 190

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hbn	NP_788420.1	Homeodomain	154..210	CDD:459649	20/55 (36%)
DPRX	NP_001012746.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..20		7/21 (33%)
		Homeodomain	18..73	CDD:459649	22/58 (38%)