Protein Alignment hbn and shox2

DIOPT Version :10

• Sequence 1: NP_788420.1
• Gene: hbn / 47894
• FlyBaseID: FBgn0008636
• Length: 409
• Species: Drosophila melanogaster
• Sequence 2: NP_957490.1
• Gene: shox2 / 394171
• ZFINID: ZDB-GENE-040426-1457
• Length: 299
• Species: Danio rerio
• Alignment Length: 233
• Identity: 85/233 - (36%)
• Similarity: 107/233 - (45%)
• Gaps: 45/233 - (19%)

  Fly   112 QAKREDSPTNTDGGLDVDNDDELSSSLNNGHDLSDMERPRKVRRSRTTFTTFQLHQLERAFEKTQ 176
            :::...||..|||..|:....|....|.:     :.:...|.|||||.||..||::|||.|::|.
Zfish    72 RSRDSSSPKLTDGNTDMKERKEDCKPLED-----ETQTKIKQRRSRTNFTLEQLNELERLFDETH 131

  Fly   177 YPDVFTREDLAMRLDLSEARVQVWFQNRRAKWRKREKFMNQDKAGYLLPEQG-------LPEFPL 234
            |||.|.||:|:.||.||||||||||||||||.||:|   ||...|.|:....       .|...:
Zfish   132 YPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQE---NQLHKGVLIGAASQFEACRVAPYVNV 193

  Fly   235 GIPLPPHGLPGH----PGSMQ--------SEFWPPHFALHQHFNPAAAAAAGLLPQHLMAPHYKL 287
            |....|.....|    |.|.|        |.....|..||.|.  ||.|...:.|    ||.:.|
Zfish   194 GALRMPFQQDSHCNVPPFSFQVQAQLQLDSAVAHAHHHLHSHL--AAHAPYMMFP----APPFGL 252

  Fly   288 PNFHTLLSQYMGLSNLNGIFGAGAAAAAAAASAGYPQN 325
            | ..||.::           .|.||:..|||:|....|
Zfish   253 P-LATLAAE-----------SASAASVVAAAAAAKTTN 278

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hbn	NP_788420.1	Homeodomain	154..210	CDD:459649	39/55 (71%)
shox2	NP_957490.1	Homeodomain	109..165	CDD:459649	39/55 (71%)
		OAR	278..295	CDD:461067	1/1 (100%)