Protein Alignment hbn and VSX2

DIOPT Version :10

• Sequence 1: NP_788420.1
• Gene: hbn / 47894
• FlyBaseID: FBgn0008636
• Length: 409
• Species: Drosophila melanogaster
• Sequence 2: NP_878314.1
• Gene: VSX2 / 338917
• HGNCID: 1975
• Length: 361
• Species: Homo sapiens
• Alignment Length: 166
• Identity: 64/166 - (38%)
• Similarity: 88/166 - (53%)
• Gaps: 6/166 - (3%)

  Fly   115 REDSPTNTDGGLDVDNDDELSSSLNNGHDLSDMERPRKVRRSRTTFTTFQLHQLERAFEKTQYPD 179
            |...|.:|......|::|..||.........:..:.||.||.||.||::||.:||:||.:..|||
Human   110 RASGPLDTSQTASSDSEDVSSSDRKMSKSALNQTKKRKKRRHRTIFTSYQLEELEKAFNEAHYPD 174

  Fly   180 VFTREDLAMRLDLSEARVQVWFQNRRAKWRKREKFMNQDKAGYLLPEQGLPEFPL--GIPLPPHG 242
            |:.||.|||:.:|.|.|:||||||||||||||||...:..   ::.|.||....:  .||||...
Human   175 VYAREMLAMKTELPEDRIQVWFQNRRAKWRKREKCWGRSS---VMAEYGLYGAMVRHSIPLPESI 236

  Fly   243 LPGHPGSMQSEFWPPHFALHQHFNPAAAAAAGLLPQ 278
            |......:.....|....:|:. :..|||.:|..|:
Human   237 LKSAKDGIMDSCAPWLLGMHKK-SLEAAAESGRKPE 271

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hbn	NP_788420.1	Homeodomain	154..210	CDD:459649	35/55 (64%)
VSX2	NP_878314.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..28
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	104..151		10/40 (25%)
		Homeodomain	153..205	CDD:459649	32/51 (63%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	262..300		5/10 (50%)
		OAR	300..318	CDD:461067
		OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138	304..317
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	313..361