DRSC/TRiP Functional Genomics Resources

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Protein Alignment hbn and rx3

DIOPT Version :9

Sequence 1:NP_788420.1 Gene:hbn / 47894 FlyBaseID:FBgn0008636 Length:409 Species:Drosophila melanogaster
Sequence 2:NP_571302.1 Gene:rx3 / 30474 ZFINID:ZDB-GENE-990415-238 Length:292 Species:Danio rerio


Alignment Length:343 Identity:106/343 - (30%)
Similarity:148/343 - (43%) Gaps:95/343 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly     2 MTTTTSQHHQHHPIMPPAMRPAPVQESPVSRPRAVYSIDQILGNQHQIKRSDTPSEVLITHPHHG 66
            |....||:......:.|:.|   :..||.|:.| ::||:.|||.:         .|.|.   |..
Zfish     1 MRLVGSQYKDMEDRLSPSAR---LVRSPGSQTR-IHSIESILGFK---------GETLF---HPA 49

  Fly    67 HPHHIHHLHSSNSNG--SNHLSHQQQQQHSQQQHHSQQQQQQQQLQVQAKREDSPTNTDG----- 124
            .|      :.|...|  :.|||                           .::||..:.||     
Zfish    50 FP------YGSGKTGKDTEHLS---------------------------PKKDSNKHFDGVCRST 81

  Fly   125 ---GLDVDNDDELSSSLNNGHDLSDMERPRKV-RRSRTTFTTFQLHQLERAFEKTQYPDVFTRED 185
               ..|:.:.|        |..|||.|.|:|. ||:||||||||||:|||||||:.||||::||:
Zfish    82 VMVSPDLPDAD--------GGKLSDDENPKKKHRRNRTTFTTFQLHELERAFEKSHYPDVYSREE 138

  Fly   186 LAMRLDLSEARVQVWFQNRRAKWRKREK-----FMNQDKAGYLLPEQGLPEFPLGIPLPPHGLPG 245
            ||::::|.|.||||||||||||||::||     ...|:.:...:|..|......|:||.| .|.|
Zfish   139 LALKVNLPEVRVQVWFQNRRAKWRRQEKLEVSSIKLQESSMLSIPRSGPLSLGSGLPLEP-WLTG 202

  Fly   246 HPGSMQSEFWPPHFALHQHFNPAAAAAAGLLPQHLMAPHYKLPNFHTLLSQYMGLSNLNGIFGAG 310
             |.|..|             :|..:..:.:.||..:...|..|       |::..|.||......
Zfish   203 -PISTSS-------------SPLQSLPSFITPQQAVPASYTPP-------QFLSSSTLNHSLPHI 246

  Fly   311 AAAAAAAASAGYPQNLSL 328
            .|.......:|:....||
Zfish   247 GAVCPPYQCSGFMDKFSL 264

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
hbnNP_788420.1 Homeobox 156..209 CDD:278475 39/52 (75%)
rx3NP_571302.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..27 7/28 (25%)
Octapeptide motif 32..39 3/6 (50%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 53..72 7/45 (16%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 85..107 9/29 (31%)
Homeobox 110..162 CDD:278475 39/51 (76%)
OAR 268..284 CDD:281777
OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138 272..285
Nuclear localization signal. /evidence=ECO:0000255 278..282
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D454642at33208
OrthoFinder 1 1.000 - - FOG0000011
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
ZFIN 00.000 Not matched by this tool.
43.880

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