Protein Alignment hbn and Nkx1-2

DIOPT Version :9

• Sequence 1: NP_788420.1
• Gene: hbn / 47894
• FlyBaseID: FBgn0008636
• Length: 409
• Species: Drosophila melanogaster
• Sequence 2: NP_033149.1
• Gene: Nkx1-2 / 20231
• MGIID: 104806
• Length: 305
• Species: Mus musculus
• Alignment Length: 233
• Identity: 69/233 - (29%)
• Similarity: 103/233 - (44%)
• Gaps: 49/233 - (21%)

  Fly    86 SHQQQQQHSQQQHHSQQQQQQQQLQVQAKREDSPTNTDGGLDVDNDDELSSSLNNGHDLSDMERP 150
            |..::::.::....:.|.::.|.:     .|.||...  .:.|..::..:..|..........||
Mouse    87 SEAEEEEEAEDAGRAHQPERWQGV-----HEGSPEAR--AVAVGTEESGAEGLPASPGSPGSPRP 144

  Fly   151 R---------KVRRSRTTFTTFQLHQLERAFEKTQYPDVFTREDLAMRLDLSEARVQVWFQNRRA 206
            |         |.||:||.||..||..||..|..|:|..|..|.:||:.|.|:|.:|::||||||.
Mouse   145 RRRRAESSCAKPRRARTAFTYEQLVALENKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRT 209

  Fly   207 KWRKREKFMNQD---KAGYLLPEQGLPEFPLG--------IPLPPHGLPGHPGSMQSEFWPPHFA 260
            ||:|:..  ..|   :||...|:.|.|....|        .|.||     .||::..:.:|.:.|
Mouse   210 KWKKQNP--GADGAVQAGGGAPQPGTPGAVAGGGGSATGSSPGPP-----VPGALPYQTFPTYPA 267

  Fly   261 LHQHFNPAAA-----AAAG------LLPQHL---MAPH 284
            .:..| |||:     ||.|      |.|.:|   .|||
Mouse   268 TNVLF-PAASFPLTTAANGSPFTPFLGPSYLTPFYAPH 304

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hbn	NP_788420.1	Homeobox	156..209	CDD:278475	26/52 (50%)
Nkx1-2	NP_033149.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	51..158		12/77 (16%)
		Homeobox	160..212	CDD:278475	26/51 (51%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	210..257		15/53 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910