DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment hbn and Rax

DIOPT Version :9

Sequence 1:	NP_788420.1	Gene:	hbn / 47894	FlyBaseID:	FBgn0008636	Length:	409	Species:	Drosophila melanogaster
Sequence 2:	NP_038861.2	Gene:	Rax / 19434	MGIID:	109632	Length:	342	Species:	Mus musculus

Alignment Length:	240	Identity:	85/240 - (35%)
Similarity:	107/240 - (44%)	Gaps:	72/240 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   144 LSDMERPRKV-RRSRTTFTTFQLHQLERAFEKTQYPDVFTREDLAMRLDLSEARVQVWFQNRRAK 207
            ||:.|.|:|. ||:||||||:|||:|||||||:.||||::||:||.:::|.|.||||||||||||
Mouse   126 LSEEEPPKKKHRRNRTTFTTYQLHELERAFEKSHYPDVYSREELAGKVNLPEVRVQVWFQNRRAK 190

  Fly   208 WRKREKFMNQDKAGYLLPEQGLPEF----------PLGIPLPPHGLPGHPGS-MQSEFW--PPHF 259
            ||::||.   :.:...|.:..|..|          |||  ..|....|.||| :..|.|  ||
Mouse   191 WRRQEKL---EVSSMKLQDSPLLSFSRSPPSSALAPLG--TGPGSGSGPPGSALPLEPWLGPP-- 248

  Fly   260 ALHQHFNPAAAAAAGLLPQHLMAPHYKLPNFHTLLSQYMGLSNLNGIFGAGAAAAAAAASAGYPQ 324
                                       ||                   |.||.|..:....|.|.
Mouse   249 ---------------------------LP-------------------GGGATALQSLPGFGPPG 267

  Fly   325 NLSLHAGLSAMSQVSPPCSNSSPRESPKLVPHPTPPHATPPAGGN 369
            .     ||.|.....||..||:|.........|.|.:...||.|:
Mouse   268 Q-----GLPASYTPPPPFLNSAPLGPGLQQLGPPPAYPCAPAFGD 307

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
hbn	NP_788420.1	Homeobox	156..209	CDD:278475	38/52 (73%)
Rax	NP_038861.2	Octapeptide motif	33..40
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	44..140		7/13 (54%)
		Homeobox	140..192	CDD:278475	38/51 (75%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	208..295		30/141 (21%)
		OAR	316..331	CDD:281777
		OAR. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00138	319..332
		Nuclear localization signal. /evidence=ECO:0000255	325..329
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D454642at33208
OrthoFinder	1	1.000	-	-		FOG0000011
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.920