Protein Alignment hbn and ARX

DIOPT Version :9

• Sequence 1: NP_788420.1
• Gene: hbn / 47894
• FlyBaseID: FBgn0008636
• Length: 409
• Species: Drosophila melanogaster
• Sequence 2: NP_620689.1
• Gene: ARX / 170302
• HGNCID: 18060
• Length: 562
• Species: Homo sapiens
• Alignment Length: 307
• Identity: 106/307 - (34%)
• Similarity: 139/307 - (45%)
• Gaps: 80/307 - (26%)

  Fly   119 PTNTDGGLDVDNDDELSSSLNNGHDLSDMERPRKVRRSRTTFTTFQLHQLERAFEKTQYPDVFTR 183
            |.:.:|     .|.|.|..|:.|.|..:....||.||.|||||::||.:|||||:||.|||||||
Human   299 PEDAEG-----KDGEDSVCLSAGSDSEEGLLKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFTR 358

  Fly   184 EDLAMRLDLSEARVQVWFQNRRAKWRKREKFMNQDKAGYLLPEQGLPEFPLGIPLPPHGLPGHPG 248
            |:|||||||:||||||||||||||||||||             .|....|.|:|.|......||.
Human   359 EELAMRLDLTEARVQVWFQNRRAKWRKREK-------------AGAQTHPPGLPFPGPLSATHPL 410

  Fly   249 S--MQSEFWPPHF-ALHQHFNPAAAAAAGLLPQHLMAPHYKLPNFHTLLSQYMGLSNLNGIFGAG 310
            |  :.:..:|||. ||...:..||||||...|.....|
Human   411 SPYLDASPFPPHHPALDSAWTAAAAAAAAAFPSLPPPP--------------------------- 448

  Fly   311 AAAAAAAASAGYPQNLSLHAGLSAMSQ---VSP----------PCSNSSPRESPKLVPHPTPPHA 362
              .:|:...:|.|..||...|.:....   :||          |.:::|  .:..|:..|||
Human   449 --GSASLPPSGAPLGLSTFLGAAVFRHPAFISPAFGRLFSTMAPLTSAS--TAAALLRQPTP--- 506

  Fly   363 TPPAGGNGGGGLLTGGLISTAAQSPNSAAGASSNASTPVSVVTKGED 409
                       .:.|.:.|.|...|.:|| |...||:..::..|.::
Human   507 -----------AVEGAVASGALADPATAA-ADRRASSIAALRLKAKE 541

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hbn	NP_788420.1	Homeobox	156..209	CDD:278475	43/52 (83%)
ARX	NP_620689.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..21
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	50..81
		GCG-encoded polyalanine repeat	102..111
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	118..255
		Homeobox	332..385	CDD:395001	44/52 (85%)
		OAR	526..544	CDD:397759	3/16 (19%)
		OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138	530..543		2/12 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D454642at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24329
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3639
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	5.020