Protein Alignment hbn and NOBOX

DIOPT Version :10

• Sequence 1: NP_788420.1
• Gene: hbn / 47894
• FlyBaseID: FBgn0008636
• Length: 409
• Species: Drosophila melanogaster
• Sequence 2: NP_001073882.3
• Gene: NOBOX / 135935
• HGNCID: 22448
• Length: 691
• Species: Homo sapiens
• Alignment Length: 137
• Identity: 29/137 - (21%)
• Similarity: 53/137 - (38%)
• Gaps: 35/137 - (25%)

  Fly   207 QAGLRLEAIVTSDVKL-----LAELTFRAKLKACPIFLVKRQTMMEWSSLTTSPGLIGIFGEPSN 266
            |.||...:.||.:.:|     ..|.|..:......:.:.|    :|.:||.||.||    |:...
Human   143 QEGLEAGSAVTGEKQLALCLQCLEKTLSSTKNRALLHIAK----LEEASLHTSQGL----GQGGT 199

  Fly   267 MSELVTRNATGSKR--LPVTVVCDNIREP------NNLGSIVRSCAAV--------------SVR 309
            .:...|.:.|..:.  |.:..:..|:..|      .:.|:::||...:              ::.
Human   200 RANQPTASWTAIEHCLLKLGEILANLSNPQLRSQAEHCGTLIRSIPTMLSVHSEQLHKTGFPTIH 264

  Fly   310 EVILLKG 316
            .:|||:|
Human   265 ALILLEG 271

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hbn	NP_788420.1	Homeodomain	154..210	CDD:459649	1/2 (50%)
NOBOX	NP_001073882.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	94..233		22/97 (23%)
		Homeodomain	273..361	CDD:459649
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	366..385
		PHA03247	<374..646	CDD:223021
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	394..437
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	635..691