Protein Alignment hbn and Crx

DIOPT Version :10

• Sequence 1: NP_788420.1
• Gene: hbn / 47894
• FlyBaseID: FBgn0008636
• Length: 409
• Species: Drosophila melanogaster
• Sequence 2: NP_001106801.1
• Gene: Crx / 12951
• MGIID: 1194883
• Length: 323
• Species: Mus musculus
• Alignment Length: 275
• Identity: 87/275 - (31%)
• Similarity: 119/275 - (43%)
• Gaps: 69/275 - (25%)

  Fly   150 PRKVRRSRTTFTTFQLHQLERAFEKTQYPDVFTREDLAMRLDLSEARVQVWFQNRRAKWRKREKF 214
            |||.||.|||||..||.:||..|.|||||||:.||::|::::|.|:||||||:|||||.|::.:.
Mouse    60 PRKQRRERTTFTRSQLEELEALFAKTQYPDVYAREEVALKINLPESRVQVWFKNRRAKCRQQRQQ 124

  Fly   215 MNQD---------------KAGYL-LPEQGLPEFPLGI--PLPPHGLPGHPGSMQS-----EFWP 256
            ..|.               |||.. .|...:...||||  ...| .|||..||..:     ..|.
Mouse   125 QKQQQQPPGAQTKARPAKRKAGTSPRPSTDVCTDPLGISDSYSP-SLPGPSGSPTTAVATVSIWS 188

  Fly   257 PHFALHQHFNPAAAAAAGLLPQHLMAPHYKLPNFHTLLSQYMGLSNLNGIFGAGAAAAAAAASAG 321
            |             |:...||:...|                      |:..:|.:..:|..:..
Mouse   189 P-------------ASEAPLPEAQRA----------------------GLVASGPSLTSAPYAMT 218

  Fly   322 YPQNLSLHAGLSAMSQVSPPCSNSSPRESPKLVPHPTPPHATPPAGGNGGGGLLTGGLISTAAQS 386
            |....:..:..||.:..|...|...|..|| :||....|..:|.:|.:.|..|         |||
Mouse   219 YAPASAFCSSPSAYASPSSYFSGLDPYLSP-MVPQLGGPALSPLSGPSVGPSL---------AQS 273

  Fly   387 PNSAAGASSNASTPV 401
            |.|.:|.|.:..:||
Mouse   274 PTSLSGQSYSTYSPV 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hbn	NP_788420.1	Homeodomain	154..210	CDD:459649	35/55 (64%)
Crx	NP_001106801.1	Homeodomain	64..117	CDD:459649	33/52 (63%)
		TF_Otx	188..273	CDD:427350	24/129 (19%)