DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment hbn and Phox2a

DIOPT Version :9

Sequence 1:	NP_788420.1	Gene:	hbn / 47894	FlyBaseID:	FBgn0008636	Length:	409	Species:	Drosophila melanogaster
Sequence 2:	NP_032913.1	Gene:	Phox2a / 11859	MGIID:	106633	Length:	280	Species:	Mus musculus

Alignment Length:	286	Identity:	81/286 - (28%)
Similarity:	102/286 - (35%)	Gaps:	133/286 - (46%)

- Green bases have known domain annotations that are detailed below.

  Fly   145 SDMERPRKVRRSRTTFTTFQLHQLERAFEKTQYPDVFTREDLAMRLDLSEARVQVWFQNRRAKWR 209
            |.:...||.||.|||||:.||.:|||.|.:|.|||::|||:||:::||:||||||||||||||:|
Mouse    82 SGLHEKRKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKFR 146

  Fly   210 KREKFMNQDKAGYLLPEQGLPEFPLGIPLPPHGLPGHPGSMQSEFWPPHFALHQHFNPAAAAAAG 274
            |:|:                                                       ||:|.|
Mouse   147 KQER-------------------------------------------------------AASAKG 156

  Fly   275 LLPQHLMAPHYKLPNFHTLLSQYMGLSNLNGIFGAGAAAAAAAASAGYPQNLSLHAGLSAMSQVS 339
                                                 ||.|..|..| ....|.....|..|..|
Mouse   157 -------------------------------------AAGATGAKKG-EARCSSEDDDSKESTCS 183

  Fly   340 P-PCSNSS-------PRESPKLVPHPTP------PHATPPAG-------GNGGGGLLTG------ 377
            | |.|.:|       ...||:|.|.|.|      |...|..|       |.||||..||
Mouse   184 PTPDSTASLPPPPAPSLASPRLSPSPLPAALGSGPGPQPLKGALWAGVAGGGGGGPGTGAAELLK 248

  Fly   378 -------------GLISTAAQSPNSA 390
                         |::|:..:.|..|
Mouse   249 AWQPAEPGPGPFSGVLSSFHRKPGPA 274

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
hbn	NP_788420.1	Homeobox	156..209	CDD:278475	36/52 (69%)
Phox2a	NP_032913.1	Homeobox	94..147	CDD:395001	36/52 (69%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	145..244		36/191 (19%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	260..280		4/15 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000011
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910