DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment hbn and Alx4

DIOPT Version :9

Sequence 1:	NP_788420.1	Gene:	hbn / 47894	FlyBaseID:	FBgn0008636	Length:	409	Species:	Drosophila melanogaster
Sequence 2:	NP_031468.1	Gene:	Alx4 / 11695	MGIID:	108359	Length:	399	Species:	Mus musculus

Alignment Length:	271	Identity:	85/271 - (31%)
Similarity:	108/271 - (39%)	Gaps:	102/271 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   132 DELSSSLNNGHDLSDMERPR-KVRRSRTTFTTFQLHQLERAFEKTQYPDVFTREDLAMRLDLSEA 195
            |..|:.:.:..:.:|.|..: |.||:|||||::||.:||:.|:||.||||:.||.||||.||:||
Mouse   180 DRASAEIPSPLEKTDSESNKGKKRRNRTTFTSYQLEELEKVFQKTHYPDVYAREQLAMRTDLTEA 244

  Fly   196 RVQVWFQNRRAKWRKREKFMNQDKAGYLLPEQGLPEFPLGIPLPPHGLPGHPGSMQSEFWPPHFA 260
            |||||||||||||||||:|                                 |.||.
Mouse   245 RVQVWFQNRRAKWRKRERF---------------------------------GQMQQ-------- 268

  Fly   261 LHQHFNPAAAAAAGLLPQHLMAPHYKLPNFHTLLSQYMGLSNLNGIFGAGAAAAAAAASAGYPQN 325
            :..||:.|                |:|| ..|....|..:.|.:.|...|||:...|...
Mouse   269 VRTHFSTA----------------YELP-LLTRAENYAQIQNPSWIGNNGAASPVPACVV----- 311

  Fly   326 LSLHAGLSAMSQVSPPCSNSSPRESPKLVPHPTPPHATPPAGG----------NGGGGLL----T 376
                           ||..         ||....|||.||..|          :|.|..:    .
Mouse   312 ---------------PCDP---------VPACMSPHAHPPGSGASSVSDFLSVSGAGSHVGQTHM 352

  Fly   377 GGLISTAAQSP 387
            |.|...|..||
Mouse   353 GSLFGAAGISP 363

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
hbn	NP_788420.1	Homeobox	156..209	CDD:278475	38/52 (73%)
Alx4	NP_031468.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	68..133
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	171..206		7/25 (28%)
		Homeobox	206..258	CDD:278475	38/51 (75%)
		OAR	375..392	CDD:281777
		OAR. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00138	379..392
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24329
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010