Protein Alignment tws and ppp2r2a

DIOPT Version :10

• Sequence 1: NP_476880.1
• Gene: tws / 47877
• FlyBaseID: FBgn0004889
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_001011075.1
• Gene: ppp2r2a / 496486
• XenbaseID: XB-GENE-971147
• Length: 444
• Species: Xenopus tropicalis
• Alignment Length: 437
• Identity: 343/437 - (78%)
• Similarity: 389/437 - (89%)
• Gaps: 3/437 - (0%)

  Fly    62 EASWCFSQIKGALDDDVTDADIISCVEFNHDGELLATGDKGGRVVIFQRDPASKAANPRRGEYNV 126
            :..|||||:|||::|||::|||||.|||||.|||||||||||||||||::..|..   .||||:|
 Frog     9 DIQWCFSQVKGAVEDDVSEADIISTVEFNHSGELLATGDKGGRVVIFQQESKSPY---HRGEYSV 70

  Fly   127 YSTFQSHEPEFDYLKSLEIEEKINKIRWLQQKNPVHFLLSTNDKTVKLWKVSERDKSFGGYNTKE 191
            |||||||||||||||||||||||||||||.|||...|||||||||:||||:|||||...|||.||
 Frog    71 YSTFQSHEPEFDYLKSLEIEEKINKIRWLPQKNAAQFLLSTNDKTIKLWKISERDKRPEGYNLKE 135

  Fly   192 ENGLIRDPQNVTALRVPSVKQIPLLVEASPRRTFANAHTYHINSISVNSDQETFLSADDLRINLW 256
            |||..|||..||.||||..:.:.|:|||||||.|||||||||||||||||.||:|||||||:|||
 Frog   136 ENGRYRDPTTVTTLRVPVFRPMDLMVEASPRRIFANAHTYHINSISVNSDYETYLSADDLRVNLW 200

  Fly   257 HLEVVNQSYNIVDIKPTNMEELTEVITAAEFHPTECNVFVYSSSKGTIRLCDMRSAALCDRHSKQ 321
            |||:.::|:|||||||.||||||||||||||||..||.||||||||||||||||.:||||||||.
 Frog   201 HLEITDRSFNIVDIKPANMEELTEVITAAEFHPHHCNTFVYSSSKGTIRLCDMRESALCDRHSKL 265

  Fly   322 FEEPENPTNRSFFSEIISSISDVKLSNSGRYMISRDYLSIKVWDLHMETKPIETYPVHEYLRAKL 386
            |||||:|:||||||||||||||||.|::||||::|||||:|:|||:||::|:|||.||||||:||
 Frog   266 FEEPEDPSNRSFFSEIISSISDVKFSHNGRYMMTRDYLSVKIWDLNMESRPVETYQVHEYLRSKL 330

  Fly   387 CSLYENDCIFDKFECCWNGKDSSIMTGSYNNFFRVFDRNSKKDVTLEASRDIIKPKTVLKPRKVC 451
            |||||||||||||||||||.|:.:||||||||||:||||:|:|:||||||:..||:|||||||||
 Frog   331 CSLYENDCIFDKFECCWNGPDNIVMTGSYNNFFRMFDRNTKRDITLEASRENSKPRTVLKPRKVC 395

  Fly   452 TGGKRKKDEISVDCLDFNKKILHTAWHPEENIIAVAATNNLFIFQDK 498
            ..||||||||:||.||||||||||||||:|||||||.||||:||||:
 Frog   396 ASGKRKKDEITVDSLDFNKKILHTAWHPKENIIAVATTNNLYIFQDR 442

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tws	NP_476880.1	CDC55	65..495	CDD:227498	339/429 (79%)
		WD40 repeat	84..132	CDD:293791	34/47 (72%)
		WD40 repeat	150..227	CDD:293791	53/76 (70%)
		WD40 repeat	233..272	CDD:293791	30/38 (79%)
		WD40 repeat	283..323	CDD:293791	33/39 (85%)
		WD40 repeat	341..377	CDD:293791	24/35 (69%)
		WD40 repeat	398..439	CDD:293791	31/40 (78%)
ppp2r2a	NP_001011075.1	CDC55	7..439	CDD:227498	339/432 (78%)
		WD40 repeat	31..76	CDD:293791	34/47 (72%)
		WD40 repeat	94..171	CDD:293791	53/76 (70%)
		WD40 repeat	177..213	CDD:293791	27/35 (77%)
		WD40 repeat	227..278	CDD:293791	42/50 (84%)
		WD40 repeat	285..321	CDD:293791	24/35 (69%)
		WD40 repeat	342..377	CDD:293791	26/34 (76%)
		WD40 repeat	416..439	CDD:293791	19/22 (86%)