Protein Alignment tws and ppp2r2d

DIOPT Version :10

• Sequence 1: NP_476880.1
• Gene: tws / 47877
• FlyBaseID: FBgn0004889
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_998045.1
• Gene: ppp2r2d / 405816
• ZFINID: ZDB-GENE-040426-2086
• Length: 447
• Species: Danio rerio
• Alignment Length: 434
• Identity: 348/434 - (80%)
• Similarity: 395/434 - (91%)
• Gaps: 0/434 - (0%)

  Fly    65 WCFSQIKGALDDDVTDADIISCVEFNHDGELLATGDKGGRVVIFQRDPASKAANPRRGEYNVYST 129
            |||||:|||:|:||.:|||||.||||:.||||||||||||||||||:..||.....|||||||||
Zfish    12 WCFSQVKGAIDEDVAEADIISTVEFNYSGELLATGDKGGRVVIFQREQESKNRPLSRGEYNVYST 76

  Fly   130 FQSHEPEFDYLKSLEIEEKINKIRWLQQKNPVHFLLSTNDKTVKLWKVSERDKSFGGYNTKEENG 194
            ||||||||||||||||||||||||||.|:|..||||||||||:||||:|||||...|||.|:|:|
Zfish    77 FQSHEPEFDYLKSLEIEEKINKIRWLPQQNAAHFLLSTNDKTIKLWKISERDKRAEGYNLKDEDG 141

  Fly   195 LIRDPQNVTALRVPSVKQIPLLVEASPRRTFANAHTYHINSISVNSDQETFLSADDLRINLWHLE 259
            .:|||..:|:||||.:..:.|:|||||||.|||||||||||||||||.||:||||||||||||||
Zfish   142 RLRDPFRITSLRVPVLMPMDLMVEASPRRIFANAHTYHINSISVNSDYETYLSADDLRINLWHLE 206

  Fly   260 VVNQSYNIVDIKPTNMEELTEVITAAEFHPTECNVFVYSSSKGTIRLCDMRSAALCDRHSKQFEE 324
            :.::|:|||||||.|||||||||||||.||.:|||||||||||||||||||:|||||||||.|||
Zfish   207 ITDRSFNIVDIKPANMEELTEVITAAECHPHQCNVFVYSSSKGTIRLCDMRAAALCDRHSKFFEE 271

  Fly   325 PENPTNRSFFSEIISSISDVKLSNSGRYMISRDYLSIKVWDLHMETKPIETYPVHEYLRAKLCSL 389
            ||:|::|||||||||||||||.|:|||||::|||||:|||||:||.:|:|||.||||||:|||||
Zfish   272 PEDPSSRSFFSEIISSISDVKFSHSGRYMMTRDYLSVKVWDLNMENRPVETYQVHEYLRSKLCSL 336

  Fly   390 YENDCIFDKFECCWNGKDSSIMTGSYNNFFRVFDRNSKKDVTLEASRDIIKPKTVLKPRKVCTGG 454
            ||||||||||||||||.||:|||||||||||:||||:::|:||||||:..||:.:||||||||||
Zfish   337 YENDCIFDKFECCWNGSDSAIMTGSYNNFFRMFDRNTRRDITLEASRESSKPRAMLKPRKVCTGG 401

  Fly   455 KRKKDEISVDCLDFNKKILHTAWHPEENIIAVAATNNLFIFQDK 498
            ||||||||||.||||||||||||||:||:|||||||||:|||||
Zfish   402 KRKKDEISVDSLDFNKKILHTAWHPKENVIAVAATNNLYIFQDK 445

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tws	NP_476880.1	CDC55	65..495	CDD:227498	343/429 (80%)
		WD40 repeat	84..132	CDD:293791	36/47 (77%)
		WD40 repeat	150..227	CDD:293791	50/76 (66%)
		WD40 repeat	233..272	CDD:293791	31/38 (82%)
		WD40 repeat	283..323	CDD:293791	34/39 (87%)
		WD40 repeat	341..377	CDD:293791	26/35 (74%)
		WD40 repeat	398..439	CDD:293791	32/40 (80%)
ppp2r2d	NP_998045.1	CDC55	7..442	CDD:227498	343/429 (80%)
		WD 1	26..65		29/38 (76%)
		WD40 repeat	31..79	CDD:293791	36/47 (77%)
		WD 2	91..132		33/40 (83%)
		WD40 repeat	97..174	CDD:293791	50/76 (66%)
		WD 3	175..213		31/37 (84%)
		WD40 repeat	180..216	CDD:293791	28/35 (80%)
		WD 4	224..264		35/39 (90%)
		WD40 repeat	230..281	CDD:293791	42/50 (84%)
		WD 5	283..321		29/37 (78%)
		WD40 repeat	288..324	CDD:293791	26/35 (74%)
		WD 6	338..379		33/40 (83%)
		WD40 repeat	345..380	CDD:293791	27/34 (79%)
		WD 7	414..447		29/32 (91%)
		WD40 repeat	419..442	CDD:293791	19/22 (86%)