Protein Alignment tws and ppp2r2ab

DIOPT Version :10

• Sequence 1: NP_476880.1
• Gene: tws / 47877
• FlyBaseID: FBgn0004889
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_001296367.1
• Gene: ppp2r2ab / 327263
• ZFINID: ZDB-GENE-030131-5474
• Length: 448
• Species: Danio rerio
• Alignment Length: 437
• Identity: 339/437 - (77%)
• Similarity: 386/437 - (88%)
• Gaps: 0/437 - (0%)

  Fly    62 EASWCFSQIKGALDDDVTDADIISCVEFNHDGELLATGDKGGRVVIFQRDPASKAANPRRGEYNV 126
            :..|||||:|||:||||.:|||||.|||||.|||||||||||||||||::..:|:....|.||||
Zfish    10 DVQWCFSQVKGAIDDDVAEADIISTVEFNHSGELLATGDKGGRVVIFQQETENKSQPQCRSEYNV 74

  Fly   127 YSTFQSHEPEFDYLKSLEIEEKINKIRWLQQKNPVHFLLSTNDKTVKLWKVSERDKSFGGYNTKE 191
            |||||||||||||||||||||||||||||.|||...|||||||||:||||:|||||...|||.||
Zfish    75 YSTFQSHEPEFDYLKSLEIEEKINKIRWLPQKNAAQFLLSTNDKTIKLWKISERDKRPEGYNLKE 139

  Fly   192 ENGLIRDPQNVTALRVPSVKQIPLLVEASPRRTFANAHTYHINSISVNSDQETFLSADDLRINLW 256
            |:|..||...:|.||||..:.:.|:|||||||.|||||||||||||||||.||:|||||||||||
Zfish   140 EDGRYRDASTITTLRVPVFRPMDLMVEASPRRVFANAHTYHINSISVNSDNETYLSADDLRINLW 204

  Fly   257 HLEVVNQSYNIVDIKPTNMEELTEVITAAEFHPTECNVFVYSSSKGTIRLCDMRSAALCDRHSKQ 321
            |||:.::|:|||||||.|||:||||||||||||.:||.||||||||||||||||::||||:|||.
Zfish   205 HLEITDRSFNIVDIKPANMEDLTEVITAAEFHPHQCNTFVYSSSKGTIRLCDMRASALCDKHSKL 269

  Fly   322 FEEPENPTNRSFFSEIISSISDVKLSNSGRYMISRDYLSIKVWDLHMETKPIETYPVHEYLRAKL 386
            |||||:|:||||||||||||||||.|::||||::|||||:|:|||:||.:|:|||.||||||:||
Zfish   270 FEEPEDPSNRSFFSEIISSISDVKFSHNGRYMMTRDYLSVKIWDLNMENRPVETYQVHEYLRSKL 334

  Fly   387 CSLYENDCIFDKFECCWNGKDSSIMTGSYNNFFRVFDRNSKKDVTLEASRDIIKPKTVLKPRKVC 451
            |||||||||||||||||||.||.:||||||||||:.||..::||||||||:..||:.|||||:||
Zfish   335 CSLYENDCIFDKFECCWNGNDSVVMTGSYNNFFRMLDRTQRRDVTLEASRESCKPRQVLKPRRVC 399

  Fly   452 TGGKRKKDEISVDCLDFNKKILHTAWHPEENIIAVAATNNLFIFQDK 498
            .||||||||||||.||||||||||||||:|||||||.||||:|||:|
Zfish   400 AGGKRKKDEISVDSLDFNKKILHTAWHPQENIIAVATTNNLYIFQEK 446

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tws	NP_476880.1	CDC55	65..495	CDD:227498	335/429 (78%)
		WD40 repeat	84..132	CDD:293791	34/47 (72%)
		WD40 repeat	150..227	CDD:293791	50/76 (66%)
		WD40 repeat	233..272	CDD:293791	31/38 (82%)
		WD40 repeat	283..323	CDD:293791	32/39 (82%)
		WD40 repeat	341..377	CDD:293791	24/35 (69%)
		WD40 repeat	398..439	CDD:293791	30/40 (75%)
ppp2r2ab	NP_001296367.1	CDC55	8..443	CDD:227498	335/432 (78%)
		WD40 repeat	32..80	CDD:293791	34/47 (72%)
		WD40 repeat	98..175	CDD:293791	50/76 (66%)
		WD40 repeat	181..217	CDD:293791	28/35 (80%)
		WD40 repeat	231..282	CDD:293791	41/50 (82%)
		WD40 repeat	289..325	CDD:293791	24/35 (69%)
		WD40 repeat	346..381	CDD:293791	25/34 (74%)
		WD40 repeat	420..443	CDD:293791	19/22 (86%)