Protein Alignment Zw10 and czw-1

DIOPT Version :10

• Sequence 1: NP_524901.2
• Gene: Zw10 / 47874
• FlyBaseID: FBgn0004643
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: NP_501327.1
• Gene: czw-1 / 177587
• WormBaseID: WBGene00017643
• Length: 778
• Species: Caenorhabditis elegans
• Alignment Length: 826
• Identity: 158/826 - (19%)
• Similarity: 309/826 - (37%)
• Gaps: 209/826 - (25%)

  Fly    46 VRKHIEDNYTEFLPNNTSPDIFLEESGSLN---------REIHDMLENL------GSEGLDALDE 95
            :.|.:::..|     :.|.|| :::.|:|.         :.|.|.||||      .:..|..|.:
 Worm    11 LEKKLKNGLT-----SISQDI-VDKYGNLKVSLNVNATAKLIFDRLENLEDIAEMSTRNLSNLID 69

  Fly    96 ANVKMAGNGRQLREILLGLGVSEHVLRIDELFQCVEE------AKAT------------KDYL-- 140
            ...|  .:...|.||.......|:::...:..:.|||      :|.|            ||:|
 Worm    70 QTAK--DSPEMLAEIKSQAQSCENLVEFLQSMKNVEEQLIIMRSKTTNRVEWGTAILACKDFLND 132

  Fly   141 --VLLDLVGRLRAFIYGDDSVDGDAQVATPEVRRIFKALECYETIKVKYHVQAYMLQQSLQERFD 203
              :||:.:||        |..|    ::.|           .:....:|.|.:|..:..|...::
 Worm   133 TNMLLEGIGR--------DGFD----MSVP-----------LKHFAAEYSVLSYNCRYQLSADYE 174

  Fly   204 RLVQLQCKSFPTSRC-----VTLQV-----SRDQTQLQDIVQALFQEPYNPARLCEFLLDNCIEP 258
            |.:.:  ......:|     |:..|     ..||..|.:.:.|:......|.||..:       .
 Worm   175 RAMNV--PKLSKQKCGDRTNVSFSVFNVGSVEDQKMLNETLSAMNMIGQLPERLDAW-------K 230

  Fly   259 VIMRPVMADYSEEADGGTYVRLSLSYATKEPSSAQLR------PNYK--------QVLENLRLL- 308
            :::..|..:....:..|..|     |....|:..|.|      |..|        :|||::.:.
 Worm   231 IVILNVFCEAIVASRDGVDV-----YIVDNPTPDQTRFLINQKPRGKKDKTIDVAKVLESMEVFF 290

  Fly   309 --LHTLAGINCSVSRDQHVF-GIIGDHVKDKMLKLLVDECLIPAVP--ESTEEYQTSTLCEDVAQ 368
              ||::...:..:......| .:||..::::::.:::.:.:..|.|  |:.:|.|...:  ::.|
 Worm   291 TKLHSVLHSHELLDATGKTFTSMIGSVIEEQLITMILKDVIAIAAPVTETADEDQEMFI--NLLQ 353

  Fly   369 LEQLLVDSFIINPEQDRALGQFVEK--------YETYYRNRMYRRVLETAREIIQRDLQDMV--- 422
            :.::.|       |:.:.||.|.:|        .:|.:..|....::..|.::|......:|
 Worm   354 IGEVFV-------ERMKELGFFSQKAKLLFTLDTDTIFVTRRCFAIVSKANKLINETYDKLVTVG 411

  Fly   423 -----------LVAPNNHSAEVAND-----------------P--FLFPRCMISKSAQDFVKLM- 456
                       |...:.|:...|.:                 |  |.|.:|.:|:|..:||.|:
 Worm   412 VDDSAIKDIDLLAKAHTHAEHFAKEYGKDLGRLWSHNEDSQFPSFFAFQKCTVSESTINFVNLLR 476

  Fly   457 DRILRQPTDKLGDQEA-DPIAGVISIMLHTYINEVPKVHRKLLESIPQQAVLFHNNCMFFTHWV- 519
            |.:  :......|:.| ..:|.....::..|:...|:.|.:|..|||..|.:|:|||.:.:|.:
 Worm   477 DNV--KAAFACEDEGARAKLALTAENIVRLYVILTPRKHAELFSSIPNMAAIFYNNCHYISHCIM 539

  Fly   520 -----AQHANK-------------GIESLAA--LAKTLQATGQQHFRVQVDYQSSILMGIMQEFE 564
                 |...|:             .:.::||  :.|||....::......|:  ||...:...::
 Worm   540 TMSFEASGDNQKTLLEPLLLDSVIRLRTVAADCMEKTLTRCRREMTAYLEDH--SIFEHLPASYK 602

  Fly   565 -----FESTHTLGSGP-----------LKLVRQCLRQLELLKNVWANVLPETVYNATFCELINTF 613
                 |.:...:....           :|.:..||..:.|:.......|.|.||......|::..
 Worm   603 TTKNTFAAAEEMSESADILVPREEPKIIKCLAACLLHIRLIAKNLREPLTEVVYCKVIGSLVSFL 667

  Fly   614 VAELIRRVFTLRDISAQMACELSDLIDVVLQRAPTL--FREPNEVVQVLS--WLKLQQLKAMLNA 674
            :..|:|.|.|..|.....|..::|:...:|:....:  ::|..:|....:  :.:|.::..:|..
 Worm   668 LDSLVRHVVTTSDFRENDANVMADVFKRLLEVVANIVAYKEQTKVTDFCAREYFRLNEIVFVLGN 732

  Fly   675 SLMEITELWGDGVGPLTASYKSDEIKHLIRALFQDTDWRAKAITQI 720
            .:.:|...|.:..||:.......|:..||:|||.|:..|:..|.::
 Worm   733 RMQDIEHRWFNAKGPMAEHLSRSEVVGLIKALFADSQHRSDLIARL 778

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Zw10	NP_524901.2	Zw10	35..519	CDD:461861	113/582 (19%)
czw-1	NP_501327.1	Zw10	11..538	CDD:461861	113/582 (19%)