Protein Alignment bgcn and hrpB

DIOPT Version :10

• Sequence 1: NP_523832.2
• Gene: bgcn / 47873
• FlyBaseID: FBgn0004581
• Length: 1215
• Species: Drosophila melanogaster
• Sequence 2: NP_414690.4
• Gene: hrpB / 944845
• ECOCYCID: EG12329
• Length: 809
• Species: Escherichia coli
• Alignment Length: 626
• Identity: 112/626 - (17%)
• Similarity: 207/626 - (33%)
• Gaps: 229/626 - (36%)

  Fly   124 LPLPAIRPPNLRFWTEAQLNFLTAFLGHSLSDEILQSLYASRVIVYNAALCWDKSVFLPLVILDD 188
            ||:.|:.|                        |:|.:|..:..::.:|.....||.:|||.:|
E. coli     4 LPVAAVLP------------------------ELLTALDCAPQVLLSAPTGAGKSTWLPLQLL-- 42

  Fly   189 CRNKKSNVKIMCIERQAILATYNSQRTANFFGEQLGETVGIQLPYFSAVSSSTFIIYSTAQYFLR 253
             .:...|.||:.:|.:.:.|...:||.|....|:.|:|||.::...:.|..:|.:...|.....|
E. coli    43 -AHPGINGKIILLEPRRLAARNVAQRLAELLNEKPGDTVGYRMRAQNCVGPNTRLEVVTEGVLTR 106

  Fly   254 SL-TSQQFRNISHLVVNDVHLHDPYTDILLSEIRMALSSHQNLR-----VVLLSQMGNPKKFTDF 312
            .: ...:...:..:::::.|......|:.|:   :.|...|.||     :::.:.:.|.:
E. coli   107 MIQRDPELSGVGLVILDEFHERSLQADLALA---LLLDVQQGLRDDLKLLIMSATLDNDR----- 163

  Fly   313 FGEGLQLNMIKQPEVAPRVSYLNELHSCIALAGIHKGPDIYKEIPEAFRANNPRNEQMDKCLQAY 377
                ||..:.:.|.|                  |.:|
E. coli   164 ----LQQMLPEAPVV------------------ISEG---------------------------- 178

  Fly   378 GELGTDAALRPFLYAVNYDLAPVNYRHSLTGKTAVHFASELNKANHLRLLLFMGADPYIVDLFQQ 442
                     |.|         ||..|:             |....|.|.               .
E. coli   179 ---------RSF---------PVERRY-------------LPLPAHQRF---------------D 197

  Fly   443 NAISLAAMNGNHECIDVLNSYSLHGYVVKSAKPDFVDYDLIIDIMYLLRTKPEYSPGEYSPGNIL 507
            :|:::|...                                     :||.:         .|::|
E. coli   198 DAVAVATAE-------------------------------------MLRQE---------SGSLL 216

  Fly   508 IILPTYYHIVKLNYMILSHCLTGSLQECSIFLLYDNMR-NDYLQALVNASDETVKVVLATDIIES 571
            :.||....|.::...:.|.  .||  :..:..||..:. ||..:|::.|.....||||||:|.|
E. coli   217 LFLPGVGEIQRVQEQLASR--IGS--DVLLCPLYGALSLNDQRKAILPAPQGMRKVVLATNIAE- 276

  Fly   572 LCLKVPFKYQIDTACRLNNVYDTTSCSGDDRFEWVAKDALLRRELILQ-----------PNKGDV 625
                        |:..:..:.....|:.:....:..:..|.|  ||.|           ...|.:
E. coli   277 ------------TSLTIEGIRLVVDCAQERVARFDPRTGLTR--LITQRVSQASMTQRAGRAGRL 327

  Fly   626 Q---CFRLISKEAYEELSETSQPSLQTMQLDKICLAVKLL----SPNTIISEYLGITISPPPLIN 683
            :   ...||:||..|..:..|:|.:  :|.|...|.::||    |....:|     .:..||::|
E. coli   328 EPGISLHLIAKEQAERAAAQSEPEI--LQSDLSGLLMELLQWGCSDPAQMS-----WLDQPPVVN 385

  Fly   684 VHHAVQFLKKIDVLDDAEDVTWLGCRLMDIPVSCQLGRMLI 724
            :..|.:.|:.:..| :.|.::..|.::..:....:|..||:
E. coli   386 LLAAKRLLQMLGAL-EGERLSAQGQKMAALGNDPRLAAMLV 425

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bgcn	NP_523832.2	DEAD-like_helicase_N	155..314	CDD:475120	35/164 (21%)
		ANKYR	<398..>460	CDD:440430	8/61 (13%)
		ANK repeat	406..438	CDD:293786	3/31 (10%)
		P-loop containing Nucleoside Triphosphate Hydrolases	465..>594	CDD:476819	25/129 (19%)
		HA2	687..789	CDD:461295	8/38 (21%)
		OB_NTP_bind	862..945	CDD:400182
hrpB	NP_414690.4	PRK11664	1..809	CDD:236950	112/626 (18%)