Protein Alignment bgcn and PRP2

DIOPT Version :10

• Sequence 1: NP_523832.2
• Gene: bgcn / 47873
• FlyBaseID: FBgn0004581
• Length: 1215
• Species: Drosophila melanogaster
• Sequence 2: NP_014408.1
• Gene: PRP2 / 855745
• SGDID: S000005294
• Length: 876
• Species: Saccharomyces cerevisiae
• Alignment Length: 862
• Identity: 165/862 - (19%)
• Similarity: 298/862 - (34%)
• Gaps: 264/862 - (30%)

  Fly   151 HSLSDEILQSLYASRVIVYNAALCWDKSVFLPLVILDDCRNKKSNVKIMCIERQAILATYNSQRT 215
            |...||:||.:..::|::........|:..||..:::|....:..::|...:.:.:.||..:.|.
Yeast   226 HQYKDELLQEIKKNQVLIIMGETGSGKTTQLPQYLVEDGFTDQGKLQIAITQPRRVAATSVAARV 290

  Fly   216 ANFFGEQLGETVGIQLPYFSAVS-SSTFIIYSTAQYFLRS-LTSQQFRNISHLVVNDVHLHDPYT 278
            |:.....||:.||.|:.:....: :.|.:.|.|....||. ||..:....|.:::::.|.....|
Yeast   291 ADEMNVVLGKEVGYQIRFEDKTTPNKTVLKYMTDGMLLREFLTDSKLSKYSCIMIDEAHERTLAT 355

  Fly   279 DILLSEIRMALSSHQNLRVVLLSQMGNPKKFTDFFGEGLQLNMIKQPEVAPRVSYLNELHSCIAL 343
            |||:..::..|.....|::::.|...|.|||::||......|:       |...|..::|
Yeast   356 DILIGLLKDILPQRPTLKLLISSATMNAKKFSEFFDNCPIFNV-------PGRRYPVDIH----- 408

  Fly   344 AGIHKGPDIYKEIPEAFRANNPRNEQMDKCLQAYGELGTDAALRPFLYAVNYDLAPVNYRHSLTG 408
                     |...|||                                         ||.|:.
Yeast   409 ---------YTLQPEA-----------------------------------------NYIHAA-- 421

  Fly   409 KTAVHFASELNKANHLRLLLFMGADPYIVDLFQQNAISLAAMNGNHECIDVLNSYSLHGYVVKSA 473
                                       |..:||                 :..:.||
Yeast   422 ---------------------------ITTIFQ-----------------IHTTQSL-------- 434

  Fly   474 KPDFVDYDLIIDIMYLLRTKPEYSPGEYSPGNILIILPTYYHI----VKLNYMILSHCLTGSLQE 534
                                         ||:||:.|.....|    .||..::..  |....::
Yeast   435 -----------------------------PGDILVFLTGQEEIERTKTKLEEIMSK--LGSRTKQ 468

  Fly   535 CSIFLLYDNMRNDYLQALVNASDETV-KVVLATDIIESLCLKVPFKYQIDTACRLNNVYD----- 593
            ..|..:|.|:..:....:...:.|.. ||||||:|.|:.......:|.||......|.|.
Yeast   469 MIITPIYANLPQEQQLKIFQPTPENCRKVVLATNIAETSLTIDGIRYVIDPGFVKENSYVPSTGM 533

  Fly   594 ----TTSCSGDDRFEWVAKDALLRRELILQPNKGDVQCFRLISKEAY-EELSETSQPSLQTMQLD 653
                |..||.      .:.|....|...:.|.|    |||:.:|.:| .||....:|.:....|.
Yeast   534 TQLLTVPCSR------ASVDQRAGRAGRVGPGK----CFRIFTKWSYLHELELMPKPEITRTNLS 588

  Fly   654 KICLAVKLLSPNTIISEYLGIT-------ISPPPLINVHHAVQFLKKIDVLDDAEDVTWLGCRLM 711
            ...|.  |||        ||:|       :..|.:..:..:::.|..:..|:....:|.||..:.
Yeast   589 NTVLL--LLS--------LGVTDLIKFPLMDKPSIPTLRKSLENLYILGALNSKGTITRLGKMMC 643

  Fly   712 DIPVSCQLGRMLIF--------GILLRCLDPILTIVSSLSTADPLGIPFTEDIDNLWDRFTIYIQ 768
            :.|...:..::|..        |:|..|    |||||.|....                 :::|.
Yeast   644 EFPCEPEFAKVLYTAATHEQCQGVLEEC----LTIVSMLHETP-----------------SLFIG 687

  Fly   769 NSIKKERTYLSDNQFSDHFIFVRLYKEWQNRMHNRTPPLYLKDEYEFMLNGLMEQLTSIRSEIVS 833
            .......:.||:.: |||.:::.::.:|:|...:|:.....|.:::.||     ::.:||:::..
Yeast   688 QKRDAAASVLSEVE-SDHILYLEIFNQWRNSKFSRSWCQDHKIQFKTML-----RVRNIRNQLFR 746

  Fly   834 SLRAANLI--HSRGKLSMNNLNQMSCNWHMVKAALTGGMYP-NIYAVDTRKSSLKSAFSG--NVS 893
            ......|:  :.:.::.:.|:... .|..:.:..::|  :| ||..:...........||  |||
Yeast   747 CSEKVGLVEKNDQARMKIGNIAGY-INARITRCFISG--FPMNIVQLGPTGYQTMGRSSGGLNVS 808

  Fly   894 MHPNTVLRDFLEPLNISAQSFRTPWIVCNRQKS-----HIVYATLVVPLAVAMFSGHPRIRLSPI 953
            :||.::|                  .|.:::|:     :::|..|       |.:....||...:
Yeast   809 VHPTSIL------------------FVNHKEKAQRPSKYVLYQQL-------MLTSKEFIRDCLV 848

  Fly   954 CDSEMSLTDRNVNVFID 970
            ...|..|.|....:|.|
Yeast   849 IPKEEWLIDMVPQIFKD 865

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bgcn	NP_523832.2	DEAD-like_helicase_N	155..314	CDD:475120	40/160 (25%)
		ANKYR	<398..>460	CDD:440430	6/61 (10%)
		ANK repeat	406..438	CDD:293786	1/31 (3%)
		P-loop containing Nucleoside Triphosphate Hydrolases	465..>594	CDD:476819	27/142 (19%)
		HA2	687..789	CDD:461295	22/109 (20%)
		OB_NTP_bind	862..945	CDD:400182	17/90 (19%)
PRP2	NP_014408.1	PTZ00121	<7..174	CDD:173412
		HrpA	223..>738	CDD:441249	136/705 (19%)
		OB_NTP_bind	775..862	CDD:400182	22/113 (19%)