Protein Alignment bgcn and ECM16

DIOPT Version :10

• Sequence 1: NP_523832.2
• Gene: bgcn / 47873
• FlyBaseID: FBgn0004581
• Length: 1215
• Species: Drosophila melanogaster
• Sequence 2: NP_013847.1
• Gene: ECM16 / 855158
• SGDID: S000004735
• Length: 1267
• Species: Saccharomyces cerevisiae
• Alignment Length: 1002
• Identity: 195/1002 - (19%)
• Similarity: 362/1002 - (36%)
• Gaps: 300/1002 - (29%)

  Fly    85 TLNMFTLLSRKSLMGKEDLELYADLVSMKANASDLPSLHLPLPAIRPPNLR--FWTEAQLNFLTA 147
            |||    :..|.::.||||:            ..|...::|   |...:.|  |:.|.
Yeast   340 TLN----IDYKPIIRKEDLD------------DGLQEAYVP---INENSTRKAFYVEV------- 378

  Fly   148 FLGHSLSDE----------------ILQSLYASRVIVYNAALCWD----KSVFLPLVI------L 186
                |.|||                |:::::.:.|::    :|.:    |:..:|..:      .
Yeast   379 ----SRSDEIQKARIQLPVFGEEHKIMEAIHHNDVVI----ICGETGSGKTTQVPQFLYEAGFGA 435

  Fly   187 DDCRNKKSNVKIMCIERQAILATYNSQRTANFFGEQLGETVGIQLPYFSAVSSSTFIIYSTAQYF 251
            :|..:....|.|  .:.:.:.|...::|.||..|:. |..||.|:.:.|.....|.:.:.|....
Yeast   436 EDSPDYPGMVGI--TQPRRVAAVSMAERVANELGDH-GHKVGYQIRFDSTAKEDTKVKFMTDGVL 497

  Fly   252 LRSLTSQ-QFRNISHLVVNDVHLHDPYTDILLS------EIRMALS-----SHQNLRVVLLSQMG 304
            ||.:... :....|.:::::.|..:..||||:.      .:|..|.     .|:.|:::::|...
Yeast   498 LREMMHDFKLTKYSSIIIDEAHERNINTDILIGMLSRCVRLRAKLHKENPIEHKKLKLIIMSATL 562

  Fly   305 NPKKFTDFFGEGLQLNMIKQPEVAPRVSYLNELHSCIALAGIHKGPDIYKEIPEAFRAN-----N 364
            ....|::        |....| :||.|..::.                 ::.|.:...|     |
Yeast   563 RVSDFSE--------NKTLFP-IAPPVLQVDA-----------------RQFPVSIHFNRRTAFN 601

  Fly   365 PRNEQMDKCLQAYGELGTDAALRPFLYAVNYDLAPVNYRHSLTGKTAV-HFASELNKANHLRLLL 428
            ..:|...|..:.:.:|...|.|                 ..|||:..: |....|.|.     ..
Yeast   602 YTDEAFRKTCKIHQKLPPGAIL-----------------VFLTGQQEITHMVKRLRKE-----FP 644

  Fly   429 FMGADPYIVDLFQQNAISLAAMNGNHECIDVLNSYSLHGYVVKSAKPDFVDYDLIIDIMYLLRTK 493
            |.....|..||  :..:|...:|.                  |:...:..|.|..:.::...:.|
Yeast   645 FKKNSKYNKDL--ETPVSKMGINS------------------KTTDLEAEDIDFSVQVIDQDKFK 689

  Fly   494 P--EYSPGEYSPGN------------------------ILIILPTYYHIVKLNYMILSHCLTGSL 532
            .  .|...|.:.||                        .|.:||.|
Yeast   690 SAIRYEEDEGNSGNGEDEEDEEEEGFEEVLTEGQTANDPLYVLPLY------------------- 735

  Fly   533 QECSIFLLYDNMRNDYLQALVNASDETVKVVLATDIIESLCLKVP-FKYQIDTACRLNNVYDTTS 596
               |:....:.||     ........:...::||::.|: .|.:| .:|.:|:.......|:.:
Yeast   736 ---SLLPTKEQMR-----VFQKPPQGSRLCIVATNVAET-SLTIPGVRYVVDSGRSKERKYNES- 790

  Fly   597 CSGDDRFE--WVAKDALLRRELILQPNKGDVQCFRLISKEAYE-ELSETSQPSLQTMQLDKICLA 658
             :|...||  ||:|.:..:|. ......|...|:||.|...:| :..:.|:|.:..|.::.|.|.
Yeast   791 -NGVQSFEVGWVSKASANQRS-GRAGRTGPGHCYRLYSSAVFEHDFEQFSKPEILRMPVESIVLQ 853

  Fly   659 VKLLSPNTIISEYLGITISPPPLINVHHAVQFLKKIDVLDDAEDVTWLGCRLMDIPVSCQLGRML 723
            :|.::.:.||:....   :||..:.:..|:|.|:.:..||:.|.:|..|.::...|:|.:..:||
Yeast   854 MKSMAIHNIINFPFP---TPPDRVALSKAIQLLQYLGALDNKEMITEDGKKMSLFPLSPRFSKML 915

  Fly   724 IFGILLRCLDPILTIVSSLSTADP------LGI--------PFTEDIDNL---WDRFTIYIQNSI 771
            :......||..|:.|||:||..||      |||        | .|::|:.   .|..|..:...:
Yeast   916 LVSDEKACLPYIVAIVSALSVGDPFINEFELGINEISRKPNP-DENLDDKIREHDESTPGMDPEL 979

  Fly   772 KKE---RTYLSDNQFS--DHFIFV-RLYK--EWQNRMHNRTPPLYLKDEYEFMLNGLMEQLTSIR 828
            |||   :.|.|.:|||  |.|..| ||..  ...:.:......:::|.  .|:...|||::..:|
Yeast   980 KKELRSKFYKSRSQFSKLDKFSDVFRLLSVVSAMDYVPKEQKEIFMKK--NFLRGKLMEEIVKLR 1042

  Fly   829 SEIVSSLRA-------ANLIHSR-------GKLSMNNLNQMSCNWHMVKAALTGGM--------- 870
            .:::..:::       |.:|.:.       ..:.:..|.||.|...:...|:...:
Yeast  1043 KQLMYIIKSNTSKENIAVVIRNEDLKSDIPSVIQIKLLKQMICAGFVDHVAVRADVLFPDDAKIT 1107

  Fly   871 -------YPNIYAVDTRKSSLKSAFSGNVSMHPNTVLRDFLEPLNISAQSFRTPWIVCNRQKSHI 928
                   .|.|..:.||..:::..|   |.:||.::|.:..|                 ....::
Yeast  1108 NRTSIINIPYIPVLATRTPNIEDCF---VYIHPTSILNNLGE-----------------MPPKYM 1152

  Fly   929 VYATLVVPLAVAMFSGHPRIRLSPICD 955
            :|.:|       ...|:.:.|::.:||
Yeast  1153 LYYSL-------HLGGNNKTRMNTLCD 1172

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bgcn	NP_523832.2	DEAD-like_helicase_N	155..314	CDD:475120	36/196 (18%)
		ANKYR	<398..>460	CDD:440430	12/62 (19%)
		ANK repeat	406..438	CDD:293786	8/32 (25%)
		P-loop containing Nucleoside Triphosphate Hydrolases	465..>594	CDD:476819	23/155 (15%)
		HA2	687..789	CDD:461295	40/123 (33%)
		OB_NTP_bind	862..945	CDD:400182	13/98 (13%)
ECM16	NP_013847.1	HrpA	390..>940	CDD:441249	126/658 (19%)
		HA2	879..1006	CDD:461295	41/127 (32%)
		OB_NTP_bind	1080..1184	CDD:400182	21/120 (18%)