Protein Alignment bgcn and DHR2

DIOPT Version :10

• Sequence 1: NP_523832.2
• Gene: bgcn / 47873
• FlyBaseID: FBgn0004581
• Length: 1215
• Species: Drosophila melanogaster
• Sequence 2: NP_012845.1
• Gene: DHR2 / 853784
• SGDID: S000001561
• Length: 735
• Species: Saccharomyces cerevisiae
• Alignment Length: 860
• Identity: 153/860 - (17%)
• Similarity: 286/860 - (33%)
• Gaps: 293/860 - (34%)

  Fly   100 KEDLELYADLVSMKANASDLPSLHLPLPAIRPPNLRFWTEAQLNFLTAFLGHSLSDEILQSLYAS 164
            ||::..|.   |:|:.||||..:...||..:... ...:..:.|.:|..:|.:.|
Yeast    58 KENVLTYK---SLKSRASDLLKMRETLPVYQHKR-EIMSYIESNPVTVLIGETGS---------- 108

  Fly   165 RVIVYNAALCWDKSVFLPLVILDDCRNKKSNVKIMCIERQAILATYNSQRTANFFGEQLGETVGI 229
                       .||..:|..:|:...:.|.:..|...:.:.:.|...:.|.|...|.:|||.||.
Yeast   109 -----------GKSTQIPQFVLEKLYDTKKHGSIAVTQPRRVAAINLATRVAQEHGCKLGEQVGY 162

  Fly   230 QLPYFSAVSSSTFIIYSTAQYFLRSL-TSQQFRNISHLVVNDVHLHDPYTDILLSEIRMALSS-H 292
            .:.:.:..::.|.:.|.|....||.| .:...|..|.:|:::.|.....||::|..::..:.. .
Yeast   163 SVRFDNTTTTRTRLKYLTDGMLLRELMMNSDLREYSVIVIDEAHERTVLTDLILGFLKSLIQGPR 227

  Fly   293 QNLRVVLLSQMGNPKKFTDFFGEGLQLNMIKQPEVAPRVSYLNELHSCIALAGIHKGPDIYKEIP 357
            .:||::::|.....:||::||
Yeast   228 PDLRIIVMSATLQAEKFSEFF-------------------------------------------- 248

  Fly   358 EAFRANNPRNEQMDKCLQAYGELGTDAALRPFLYAVNYDLAPVNYRHSLTGKTAVHFASELNKAN 422
                 ||                                 ||:
Yeast   249 -----NN---------------------------------API---------------------- 253

  Fly   423 HLRLLLFMGADPYIVDLFQQNAISLAAMNGNHECIDVLNSYSLHGYVVKSAKPDFVDYDLIIDIM 487
                            ||.:.                 ..:.:..|.:|:...|.||
Yeast   254 ----------------LFVEG-----------------RKFDVKQYYLKAPTDDIVD-------- 277

  Fly   488 YLLRTKPEYSPGEYSPGNILIILPTYYHIVK--------LNY--------MILSHCLTGSL---Q 533
            .::|...:.:.|| ..|:||..||....|.|        ..|        :|:.:.|..:|   |
Yeast   278 AVIRCCIQINQGE-ELGDILCFLPGQEEIDKAVTIMEKIAKYVSDEAPVPLIVPYPLYAALPAVQ 341

  Fly   534 ECSIFLLYDNMRNDYLQALVNASDETVKVVLATDIIESLCLKVPFKYQIDTACRLNNVYDTTSCS 598
            :..:|......:.              |||.:|:|.|:.......|:.:|:..|...|:
Yeast   342 QSLVFAPIKGFKR--------------KVVFSTNIAETSVTISGVKFVVDSGLRKVKVW------ 386

  Fly   599 GDDRFEWVAKDALLRRELILQP--------------NKGDVQCFRLISKEAYEELSETSQPSLQT 649
                     :..|....|:..|              .:.:.:.|||..:..|.:|.:.|:|.:..
Yeast   387 ---------RHQLGLATLLTVPISQASAMQRSGRAGRESEGKSFRLYCESDYVKLPKQSEPEIAR 442

  Fly   650 MQLDKICLAVKLLSPNTIISEYLGIT-ISPPPLINVHHAVQFLKKIDVLDDAEDVTWLGCRLMDI 713
            ..:....|.:|...    :.:.|..| ...|....:...:|.|.::..||....:|..|.::..:
Yeast   443 SDVTSPVLMLKRYG----VDDLLNWTWFENPGKEAIVMGLQELYELGALDTRGKITKRGQQMALL 503

  Fly   714 PVSCQLGRMLIFGILLRCLDPILTIVSSLSTADPLGIPFTEDIDNLWDRFTIYIQNSIKKERTYL 778
            |:...|..:||....:.||..::.|||.||..:.|..|..|:.|.:.:| .:.:.|:.|:
Yeast   504 PLQPHLSSVLIKASEVGCLSQVIDIVSCLSVENLLLNPSPEERDEVNER-RLSLCNAGKR----- 562

  Fly   779 SDNQFSDHFIFVRLYKEWQNRMHNRTPPLYLKDEYEFMLNGLMEQLTSIRSE----IVSSLRA-A 838
                :.|..:...|:                 |.|.:.| |..:..:|.|::    :..|:|. .
Yeast   563 ----YGDLIMLKELF-----------------DIYFYEL-GKSQDASSERNDWCKGLCISIRGFK 605

  Fly   839 NLIHSRGKL---------SMNNLNQMSCN--------WHMVKAALTGGMYPNIYAVDTRKSSLKS 886
            |:|..|.:|         |::..::.|..        ..::|..|||  :....|:.....|.::
Yeast   606 NVIRVRDQLRVYCKRLFSSISEEDEESKKIGEDGELISKILKCFLTG--FIKNTAIGMPDRSYRT 668

  Fly   887 AFSGN-VSMHPNTVL 900
            ..:|. :|:||:::|
Yeast   669 VSTGEPISIHPSSML 683

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bgcn	NP_523832.2	DEAD-like_helicase_N	155..314	CDD:475120	34/160 (21%)
		ANKYR	<398..>460	CDD:440430	4/61 (7%)
		ANK repeat	406..438	CDD:293786	0/31 (0%)
		P-loop containing Nucleoside Triphosphate Hydrolases	465..>594	CDD:476819	31/147 (21%)
		HA2	687..789	CDD:461295	25/101 (25%)
		OB_NTP_bind	862..945	CDD:400182	11/40 (28%)
DHR2	NP_012845.1	HrpA	79..>534	CDD:441249	109/655 (17%)
		OB_NTP_bind	645..722	CDD:400182	11/41 (27%)