Protein Alignment bgcn and YLR419W

DIOPT Version :10

• Sequence 1: NP_523832.2
• Gene: bgcn / 47873
• FlyBaseID: FBgn0004581
• Length: 1215
• Species: Drosophila melanogaster
• Sequence 2: NP_013523.3
• Gene: YLR419W / 851137
• SGDID: S000004411
• Length: 1435
• Species: Saccharomyces cerevisiae
• Alignment Length: 837
• Identity: 163/837 - (19%)
• Similarity: 320/837 - (38%)
• Gaps: 202/837 - (24%)

  Fly    95 KSLMGKEDLELYADLVSMKANASDLPSLHL---PLPAIRPPNLRFWTEAQLNFLTAFLGHSLSDE 156
            |:.:.::.|.:..:..:.:..:|:..|:.|   .|||        |.:.::
Yeast   570 KTTISEDTLSVLREEYTKRIKSSEYKSMQLVREQLPA--------WKKQKV-------------- 612

  Fly   157 ILQSLYASRVIVYNAALCWDKSVFLPLVILDDCRNKKSN---VKIMCIERQAILATYNSQRTANF 218
            |:..:..:.|::........||..:...|||..:.:|.:   .||:|.:.:.|.|...::|.::.
Yeast   613 IIDIINKNEVVLITGETGSGKSTQVVQFILDFLQKEKGDFGKTKIVCTQPRRISAIGLAERVSDE 677

  Fly   219 FGEQLGETVGIQLPYFSAVSSSTFIIYSTAQYFLRSLTSQQFRNI---SHLVVNDVHLHDPYTDI 280
            .....||.||..:...:...:||.|.:.|....:|.|  |..|.:   :.:|:::||.....||:
Yeast   678 RCVTCGEEVGYVIRGVNKTKASTRIKFMTTGVLVRLL--QNARTMLENTIVVIDEVHERSIDTDL 740

  Fly   281 LLSEIRMALSSHQNLRVVLLSQMGNPKKFTDFFGEGLQLNMIKQPEVAPRVSYLNELHSCIALAG 345
            :::.::..|...:.:::||:|...|...|..|| .||....| :....|...|..|
Yeast   741 IVTLMKNLLHRVRGMKIVLMSATVNVDLFKKFF-PGLATCHI-EGRTFPITDYFLE--------- 794

  Fly   346 IHKGPDIYKEIPEAFRANNPRNEQMDKCLQAYGELGTDAALRPFLYAVNYDLAPVNYRHSLTGKT 410
                 ||..::.  |:....:                         |::||...|:.|::
Yeast   795 -----DILSDLD--FKIKREK-------------------------ALSYDDDSVDERNN----- 822

  Fly   411 AVHFASELNKANHLRLLLFMGADPYIVDLFQQNAISLAAMNGNHECIDVLNSYSLHGYVVKSAKP 475
                                 .|.|:    :..|.|....:|.
Yeast   823 ---------------------DDQYL----KPRADSKFFTSGQ---------------------- 840

  Fly   476 DFVDYDLIIDIMYLLRTKPEYSPGEYSPGNILIILPTYYHIVKLNYMILSHCLTGSLQECSIFLL 540
              ::|||:..::..:..:.:.:...   |:|::.||.                .|.:.:|...|.
Yeast   841 --INYDLLCQVVEYVHKRLKAANDN---GSIIVFLPG----------------VGEINKCCNLLA 884

  Fly   541 YDNMRNDYL-----QALVNASDETV--------KVVLATDIIESL-----CLKVPFKYQIDTACR 587
            ..:...|::     .||.....:.|        |||::|:|.|:.     |:..     |||...
Yeast   885 NKSNEADFMVLPLHSALTPEDQKRVFKKYHGKRKVVVSTNIAETSITIDDCVAT-----IDTGRA 944

  Fly   588 LNNVYDTTSCSGDDRFEWVAKDALLRRELILQPNKGDVQ---CFRLISKEAYE-ELSETSQPSLQ 648
            .:..|:....:......:::|..:.:|    :...|.|:   .::|.||..|| ::.....|.::
Yeast   945 KSMFYNPKDNTTKLIESFISKAEVKQR----RGRAGRVREGLSYKLFSKNLYENDMISMPIPEIK 1005

  Fly   649 TMQLDKICLAVKLLSPNTIISEYLGITISPPPLINVHHAVQFLKKIDVLDDAE-DVTWLGCRLMD 712
            .:.|:.:.|:||.:.... :..:|...:..|||..:..|.:.|..|.::|::: .:|.||..:..
Yeast  1006 RIPLESLYLSVKAMGIKD-VKAFLSTALDAPPLPALQKAERILTTIGLVDESDKSLTQLGQFISL 1069

  Fly   713 IPV-SCQLGRMLIFGILLRCLDPILTIVSSLSTADPLGI-PFTEDIDNLWDRFTIYIQNSIKKER 775
            :|| ..:.|::||:|||..|.|..:.:||.|.    :|: ||....:|         :..|||
Yeast  1070 MPVMDSKHGKLLIYGILFGCTDISVLLVSILG----IGVLPFIGGFEN---------REKIKK-- 1119

  Fly   776 TYLSDNQFSDHFIFVRLYKEWQNRMHNRTPPLYLKDEYEFMLNGLMEQLTSIRSEIVSSLRAANL 840
            .........|.|..:.:.:::.....:.....||:|  ..:....:.::.|..::..|.|:....
Yeast  1120 LLCKYESRGDLFAVLEIVRDYFKIKDSSIKRKYLRD--NLLSYNKINEIKSSTAQYYSILKDVGF 1182

  Fly   841 IHSRGKL-SMNNLNQMSCNWHMVKAALTGGMYPNIYAVDTRKSSLKSAFSGNVSMHP 896
            :....|: |:::||:...|:.:::|.|||..||:|..|........|..||.|...|
Yeast  1183 LPMDYKVGSISDLNRNERNFDILRAILTGAFYPHIARVQLPDVKYLSTSSGAVEKDP 1239

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bgcn	NP_523832.2	DEAD-like_helicase_N	155..314	CDD:475120	38/164 (23%)
		ANKYR	<398..>460	CDD:440430	7/61 (11%)
		ANK repeat	406..438	CDD:293786	2/31 (6%)
		P-loop containing Nucleoside Triphosphate Hydrolases	465..>594	CDD:476819	25/146 (17%)
		HA2	687..789	CDD:461295	29/104 (28%)
		OB_NTP_bind	862..945	CDD:400182	13/35 (37%)
YLR419W	NP_013523.3	UBA_YLR419W_like	369..409	CDD:270457
		RWD_YLR419W-like	428..532	CDD:467662
		HrpA	600..>1219	CDD:441249	152/785 (19%)
		OB_NTP_bind	1205..>1342	CDD:400182	13/35 (37%)