DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment bgcn and AT2G01130

DIOPT Version :9

Sequence 1:	NP_523832.2	Gene:	bgcn / 47873	FlyBaseID:	FBgn0004581	Length:	1215	Species:	Drosophila melanogaster
Sequence 2:	NP_178223.2	Gene:	AT2G01130 / 814642	AraportID:	AT2G01130	Length:	1113	Species:	Arabidopsis thaliana

Alignment Length:	995	Identity:	248/995 - (24%)
Similarity:	392/995 - (39%)	Gaps:	224/995 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   124 LPLPAI-----RPPNLR----FW---TEAQ--LNFLTAFLGHSLSDEILQSLYASRVIVYNAALC 174
            ||:.|.     |...||    :|   .|.|  |:..|:.........:|.::..::|||.:....
plant   182 LPISATKILWQRSLQLRDRQQYWQASVEGQRMLDSRTSLPAFKQRHSVLTAISQNQVIVISGETG 246

  Fly   175 WDKSVFLPLVILDD--CRNKKSNVKIMCIERQAILATYNSQRTANFFGEQLGETVGIQLPYFSAV 237
            ..|:..:|..||:.  ..|:.:...|:|.:.:.|.|...|:|.|...||||||:||.::......
plant   247 CGKTTQIPQFILESEIEANRGAFSSIICTQPRRISAMSVSERVAYERGEQLGESVGYKVRLEGVK 311

  Fly   238 SSSTFIIYSTAQYFLRS-LTSQQFRNISHLVVNDVHLHDPYTDILLSEIRMALSSHQNLRVVLLS 301
            ...|.:::.|....||. |..:..|.::|::|:::|......|.||..::..||....|:::|:|
plant   312 GRDTRLLFCTTGILLRRLLVDRNLRGVTHVIVDEIHERGMNEDFLLIILKDLLSRRSELKLILMS 376

  Fly   302 QMGNPKKFTDFFGEGLQLNMIKQPEVAPRVSYLNELHSCIALAGIHKGPDIYKEIPEAFRANNPR 366
            ...:.:.|:.:|| |..:..|      |..:|....|             ..::|.|..|.....
plant   377 ATLDAELFSSYFG-GAGVIYI------PGFTYPVRSH-------------FLEDILEMTRYRLTP 421

  Fly   367 NEQMDKCLQAYGELGTDAALRPFLYAVNYDLAPVNYRHSLTGKTAVHFASELNKANHLRLLLFMG 431
            ..|:|.    ||:..|        :.:|..:....       |:.:.|..|    :.||...|..
plant   422 YNQIDD----YGQERT--------WKMNKQIPKKR-------KSQITFVVE----DALRAADFKE 463

  Fly   432 ADPYIVDLFQQNAISLAAMNGNHECIDVLNSYSLHGYVVKSAKPDFVDYDLIIDIMYLLRTKPEY 496
            ..|                    |..:.|:.:          .||.:.::|   |.:||....|
plant   464 FSP--------------------ETRESLSCW----------YPDCIGFNL---IEFLLCNICE- 494

  Fly   497 SPGEYSPGNILIILPTYYHIVKLNYMILSHCLTGSLQECSIFLLYDNMRNDYLQALV--NASDET 559
               ...||.|||.|..:..|..|...:..|.:.|:.....:...:.:|.. :.|.|:  ..:...
plant   495 ---NEGPGGILIFLTGWDDISSLKEKLQIHPIFGNPDLVMLLACHGSMET-FEQRLIFEEPASGV 555

  Fly   560 VKVVLATDIIESLCLKVPFKYQIDTACRLNNVYD---TTSCSGDDRFEWVAKDALLRRELILQPN 621
            .|:||||:|.|:........:.||........||   .|.|...   .|::|.:..:|    :..
plant   556 RKIVLATNIAETSITINDVAFVIDCGKAKETSYDALNNTPCLLP---SWISKVSAQQR----RGR 613

  Fly   622 KGDV---QCFRLISKEAYEELSETSQPSLQTMQLDKICLAVKLLSPNTIISEYLGITISPPPLIN 683
            .|.|   ||:.|..|..|:..:|...|.:....|..:||.:|.|:..: |||:|...:..|.|:.
plant   614 AGRVRPGQCYHLYPKCVYDAFAEYQLPEILRTPLHSLCLQIKSLNLGS-ISEFLSRALQSPELLA 677

  Fly   684 VHHAVQFLKKIDVLDDAEDVTWLGCRLMDIPVSCQLGRMLIFGILLRCLDPILTIVSSLSTADPL 748
            |..|:.|||.|..||:.||:|.||..|..:|:..:||:|||.|.:|.|||||||:.:.||..||.
plant   678 VQKAIAFLKIIGALDENEDLTTLGRYLSKLPMEPKLGKMLILGAILGCLDPILTVAAGLSVRDPF 742

  Fly   749 GIPFTEDIDNLWDRFTIYIQNSIKKERTYLSDNQF----SDHFIFVRLYKEWQNRMHNRTPPLYL 809
            ..|  :|                ||:....:.:||    |||...||.|:.|:
plant   743 LTP--QD----------------KKDLAEAAKSQFSRDHSDHLALVRAYEGWK------------ 777

  Fly   810 KDEYE----------FMLNGLMEQLTSIRSEIVSSLRAANLIHSRGKLSMNNLNQMSCNWHMVKA 864
            |.|.|          |:....:..:.|:|.|..|.|:...||.  |..|:.|......|  :.:|
plant   778 KAEEESAVYDYCWKNFLSIQSLRAIDSLRKEFFSLLKDTGLID--GNPSICNSEGNDAN--LTRA 838

  Fly   865 ALTGGMYPNIYAV--DTRKSSLKSAFSGNVSMHPNTVLRDFLEPLNISAQSFRTPWIVCNRQ-KS 926
            .:..||||.|.:|  :.|..|||:...|.|.::.|:.        |........||:|.|.: |.
plant   839 VICYGMYPGICSVVHNERSFSLKTMEDGQVLLYSNSE--------NARETKIPYPWLVFNEKIKV 895

  Fly   927 HIVYATLVVPLAVAMFSGHPRIRLSPIC-DSEMSL---------TDRNVNVFIDEWIWMVMSKAT 981
            :.|:                 :|.|..| ||.:.|         ||.::.: :..::...|....
plant   896 NSVF-----------------LRDSTACSDSTLILFGGSISKGDTDGHLKM-LGGYLEFFMKPDV 942

  Fly   982 AEMVMRTRYYFFKMYHDLLKHCSELDMWRRDCEPVSQYTVLTDTLS--KIFESEDGFVGFF---- 1040
            ||           :|..|.|...|| :..:...|........:.||  ::..||||..|.|
plant   943 AE-----------IYQTLKKELDEL-IQNKLLNPKVDMQAHRELLSAIRLLVSEDGCDGRFVFGH 995

  Fly  1041 ---KPPPITFLPTPQLPSLY 1057
               :|..|:.|.|.  |||:
plant   996 QILRPLEISALSTK--PSLF 1013

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bgcn	NP_523832.2	ANK repeat	406..438	CDD:293786	7/31 (23%)
		ANK	407..>460	CDD:238125	8/52 (15%)
		Ank_2	413..>460	CDD:289560	7/46 (15%)
		HrpA	<484..973	CDD:224557	143/523 (27%)
		HA2	694..763	CDD:214852	30/68 (44%)
		OB_NTP_bind	823..945	CDD:285018	32/124 (26%)
AT2G01130	NP_178223.2	DEXDc	225..402	CDD:214692	47/183 (26%)
		DEXDc	237..379	CDD:238005	40/141 (28%)
		Helicase_C	488..617	CDD:278689	33/140 (24%)
		HA2	688..770	CDD:214852	37/99 (37%)
		OB_NTP_bind	807..918	CDD:285018	36/139 (26%)
		dsrm	1025..1087	CDD:278464
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1643
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810