Protein Alignment bgcn and Dhx30

DIOPT Version :10

• Sequence 1: NP_523832.2
• Gene: bgcn / 47873
• FlyBaseID: FBgn0004581
• Length: 1215
• Species: Drosophila melanogaster
• Sequence 2: NP_001239612.1
• Gene: Dhx30 / 72831
• MGIID: 1920081
• Length: 1223
• Species: Mus musculus
• Alignment Length: 869
• Identity: 193/869 - (22%)
• Similarity: 321/869 - (36%)
• Gaps: 256/869 - (29%)

  Fly   155 DEILQSLYASRVIVYNAALCWDKSVFLPLVILD----DCRNKKSNVKIMCIERQAILATYNSQRT 215
            |.||.::....|:|.:......|:..:|.::|:    :.|..:.||.|  .:.:.|.|...:||.
Mouse   470 DTILSAIEQHPVVVISGDTGCGKTTRIPQLLLERYVTEGRGARCNVII--TQPRRISAVSVAQRV 532

  Fly   216 ANFFGEQLGETVGIQLPYFS-AVSSSTFIIYSTAQYFLRSLTSQ-QFRNISHLVVNDVHLHDPYT 278
            ::..|..|...||.|:...| ..:....:::.|....||.|.|. ....:||::|::||..|..|
Mouse   533 SHELGPSLRRNVGFQVRLESKPPARGGALLFCTVGILLRKLQSNPSLEGVSHVIVDEVHERDVNT 597

  Fly   279 DILLSEIRMALSSHQNLRVVLLSQMGNPKKFTDFFGEGLQLNMIKQPEVAPRVS--YLNELHSCI 341
            |.||..::.....:..||:||:|..|:.::|:.:||   ...:||.|.....|.  ||.::   :
Mouse   598 DFLLILLKGLQRLNPALRLVLMSATGDNERFSRYFG---GCPVIKVPGFMYPVKEHYLEDI---L 656

  Fly   342 ALAGIHKGPDIYKEIPEAFRANNPRNEQMDKCLQAYGELGTDAALRPFLYAVNYDLAPVNYRHSL 406
            |..|.|:.|                                                   :||.
Mouse   657 AKLGKHQYP---------------------------------------------------HRHR- 669

  Fly   407 TGKTAVHFASELNKANHLRLLLFMGADPYIVDLFQQNAISLAAMNGNHECIDVLNSYSLHGYVVK 471
                  |..||                                    .||.
Mouse   670 ------HHESE------------------------------------DECA-------------- 678

  Fly   472 SAKPDFVDYDLIIDIMYLLRTKPEYSPGEYSPGNILIILPTYYHIV-------------KLNYMI 523
                  :|.||:.|::..:..:.|       ||.||..||.:..|.             :..|:|
Mouse   679 ------LDLDLVTDLVLHIDARGE-------PGGILCFLPGWQEIKGVQQRLQEALGMHESKYLI 730

  Fly   524 LS-HCLTGSLQECSIFLLYDNMRNDYLQALVNASDETVKVVLATDIIESLCLKVPFKYQIDTACR 587
            |. |.....:.:.:||          .|..:...    |:||||:|.|:........:.:|:...
Mouse   731 LPVHSNIPMMDQKAIF----------QQPPLGVR----KIVLATNIAETSITVNDIVHVVDSGLH 781

  Fly   588 LNNVYD---TTSCSGDDRFEWVAKDALLRRELILQPNKGDVQ---CFRLISKEAYEELSETSQPS 646
            ....||   ..||.   ...||::..:::|    :...|..|   .:.|..:...|::.....|.
Mouse   782 KEERYDLKTKVSCL---ETVWVSRANVIQR----RGRAGRCQSGFAYHLFPRSRLEKMVPFQVPE 839

  Fly   647 LQTMQLDKICLAVKLLSPNTIISEYLGITISPPPLINVHHAVQFLKKIDVLDDAEDVTWLGCRLM 711
            :....|:.:.|..|:..|.....|:|...:..|.:..|..||..|::|.|||..|.:|.||.||.
Mouse   840 ILRTPLENLVLQAKIHMPEKTAVEFLSKAVDSPNIKAVDEAVILLQEIGVLDQREYLTTLGQRLA 904

  Fly   712 DIPVSCQLGRMLIFGILLRCLDPILTIVSSLSTADPLGIPFTEDIDNLWDRFTIYIQNSIKKERT 776
            .|....:|.:.::...:.|||.|:|.:||.| |.|    ||:..:.|         :..:.|.:.
Mouse   905 HISTDPRLAKAIVLAAIFRCLHPLLVVVSCL-TRD----PFSSSLQN---------RAEVDKVKA 955

  Fly   777 YLSDNQFSDHFIFVRLYKEWQN--RMHNRTP-PLYLKDEYEF-----MLNGLMEQLTSIRSEIVS 833
            .||.:..|||..|||....|:.  |..:||. ..||::...:     .::||::|.:       .
Mouse   956 LLSHDSGSDHLAFVRAVAGWEEVLRWQDRTSRENYLEENLLYAPSLRFIHGLIKQFS-------E 1013

  Fly   834 SLRAANLIHSRGKLSMNNLNQMSCNWH-----MVKAALTGGMYPNIYAVDTRKSSLKSAF----- 888
            ::..|.|:   ||.|...|....||.:     :||..|..|:|||:..|...|.:.:..|
Mouse  1014 NIYEAFLV---GKPSDCTLPSAQCNEYSEEEELVKGVLMAGLYPNLIQVRQGKVTRQGKFKPNSV 1075

  Fly   889 -----SGNVSMHPNTVLRDFLEPLNISAQSFRTPWI-----VCNRQKSHIVYATLVVPLAVAMFS 943
                 |||:.:|.:|:.|:        |...|:.|:     |.:.....:..::.|.||||.:
Mouse  1076 TYRTKSGNILLHKSTINRE--------ATRLRSRWLTYFMAVKSNGSVFVRDSSQVHPLAVLL-- 1130

  Fly   944 GHPRIRLSPICDSEMSLTDRNVNV 967
                            |||.:|::
Mouse  1131 ----------------LTDGDVHI 1138

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bgcn	NP_523832.2	DEAD-like_helicase_N	155..314	CDD:475120	44/164 (27%)
		ANKYR	<398..>460	CDD:440430	7/61 (11%)
		ANK repeat	406..438	CDD:293786	3/31 (10%)
		P-loop containing Nucleoside Triphosphate Hydrolases	465..>594	CDD:476819	29/145 (20%)
		HA2	687..789	CDD:461295	34/101 (34%)
		OB_NTP_bind	862..945	CDD:400182	25/97 (26%)
Dhx30	NP_001239612.1	HrpA	455..>987	CDD:441249	151/680 (22%)
		OB_NTP_bind	1044..1131	CDD:400182	25/112 (22%)