Protein Alignment bgcn and Dhx40

DIOPT Version :10

• Sequence 1: NP_523832.2
• Gene: bgcn / 47873
• FlyBaseID: FBgn0004581
• Length: 1215
• Species: Drosophila melanogaster
• Sequence 2: NP_080467.3
• Gene: Dhx40 / 67487
• MGIID: 1914737
• Length: 779
• Species: Mus musculus
• Alignment Length: 772
• Identity: 151/772 - (19%)
• Similarity: 252/772 - (32%)
• Gaps: 245/772 - (31%)

  Fly   212 SQRTANFFGEQLGETVGIQLPYFSAVSSSTFIIYSTAQYFLRS-LTSQQFRNISHLVVNDVHLHD 275
            :||.|......||..||.|:.:....|..|.|.|.|....|:. |........|.:::::.|...
Mouse   115 AQRVAEEMKCTLGSKVGYQVRFDDCSSKETAIKYMTDGCLLKHILGDPNLSKFSVIILDEAHERT 179

  Fly   276 PYTDILLSEIRMAL-----SSHQNLRVVLLSQMGNPKKFTDFFGEGLQLNMIKQPEVAPRVSYLN 335
            ..||||...::...     :..::|:||::|......|.:.|||
Mouse   180 LTTDILFGLLKKLFQDKSPNRKEHLKVVVMSATMELAKLSAFFG--------------------- 223

  Fly   336 ELHSCIALAGIHKGPDIYKEIPEAF-RANNPRNEQMDKCLQAYGELGTDAALRPFLYAVNYDLAP 399
               :|    .|...|.....:.|.| ....||:.:....:||..::..|..|......:..
Mouse   224 ---NC----PIFDIPGRLYPVREKFCNLIGPRDRENTAYIQAIVKVTMDIHLNEMAGDILV---- 277

  Fly   400 VNYRHSLTGKTAVHFASELNKANHLRLLLFMGADPYIVDLFQQNAISLAAMNGNHECIDVLNSYS 464
                 .|||:..:..:.||                    |||.
Mouse   278 -----FLTGQFEIEKSCEL--------------------LFQM---------------------- 295

  Fly   465 LHGYVVKSAKPDFVDYDLIIDIMYLLRTKPEYSPGEYSPGNILIILPTYYHIVKLNYMILSHCLT 529
                      .:.||||..:....|               :.|:|||.|
Mouse   296 ----------AESVDYDYDVQDTTL---------------DGLLILPCY---------------- 319

  Fly   530 GSLQECSIFLLYDNMRNDYLQALVNASDETVKVVLATDIIESLCLKVPFKYQIDTAC--RLNNVY 592
            ||:..       |..|..:|.......    |.|::|:|..:.......:|.:|...  :||:
Mouse   320 GSMTT-------DQQRRIFLPPPPGIR----KCVISTNISATSLTIDGIRYVVDGGFVKQLNH-- 371

  Fly   593 DTTSCSGDDRFEWV---AKDALLRRELILQPNKGDVQCFRLISKEAYEE-LSETSQPSLQTMQLD 653
              ....|.|..|.|   ..:||.|.....:...|  :|||:.|||.:.: :.:...|.::...|.
Mouse   372 --NPRLGLDILEVVPISKSEALQRSGRAGRTASG--KCFRIYSKEFWSQCMPDHVIPEIKRTSLT 432

  Fly   654 KICLAVKLLSPNTIIS-EYLGITISPPPLINVHHAVQFLKKIDVLDDAEDVTWLGCRLMDIPVSC 717
            .:.|.:|.|:.:.:|. .||    .||....:..|::.|.:.|.:|.:..||.||..:::.|:..
Mouse   433 SVVLTLKCLAIHDVIRFPYL----DPPNERLILEALKQLYQCDAIDRSGHVTRLGLSMVEFPLPP 493

  Fly   718 QLGRMLIFGILLRCLDPILTIVSSLSTADPLGIPFTEDIDNLWDRFTIYIQNSIKKERTYLSDNQ 782
            .|...:|....|.|.|.:|.|.:.||                       ::|
Mouse   494 HLTCAVIRAASLDCEDLLLPIAAMLS-----------------------VEN------------- 522

  Fly   783 FSDHFIFVR-LYKEWQNRMHNRTPPLYLK----DEYEFMLNGLMEQLTSIRSEIVSSLRAANLIH 842
                 :|:| :..|:|.....|...|..|    :::. .|..:.||..|  |...:|....:.||
Mouse   523 -----VFIRPVDPEYQKEAEQRHRELAAKAGGFNDFA-TLAVIFEQCKS--SGAPASWCQKHWIH 579

  Fly   843 SRGKLS-----------MNNLNQMS---------CNWHMVKAALTGGMYPNIYAVDTRKSSLKSA 887
            .|...|           :..|.|.|         ....:::..|..|.:.|:     .:.|:...
Mouse   580 WRCLFSAFRVEAQLRELIRKLKQQSDFPRETFEGPKHEVLRRCLCAGYFKNV-----ARRSVGRT 639

  Fly   888 F------SGNVSMHPNTVLRDFLEPLNISAQSFRTPWIVCNR-QKSHIVYATLVVPL 937
            |      ...|.:||::.|.:         |..:..||:.:. ..:..|||.:|.|:
Mouse   640 FCTMDGRGSPVHIHPSSALHE---------QETKLEWIIFHEVLVTTKVYARIVCPI 687

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bgcn	NP_523832.2	DEAD-like_helicase_N	155..314	CDD:475120	27/107 (25%)
		ANKYR	<398..>460	CDD:440430	8/61 (13%)
		ANK repeat	406..438	CDD:293786	5/31 (16%)
		P-loop containing Nucleoside Triphosphate Hydrolases	465..>594	CDD:476819	23/130 (18%)
		HA2	687..789	CDD:461295	19/101 (19%)
		OB_NTP_bind	862..945	CDD:400182	17/83 (20%)
Dhx40	NP_080467.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..53
		HrpA	51..>699	CDD:441249	151/772 (20%)
		DEAH box	173..176		0/2 (0%)