Protein Alignment bgcn and DHX32

DIOPT Version :9

• Sequence 1: NP_523832.2
• Gene: bgcn / 47873
• FlyBaseID: FBgn0004581
• Length: 1215
• Species: Drosophila melanogaster
• Sequence 2: NP_060650.2
• Gene: DHX32 / 55760
• HGNCID: 16717
• Length: 743
• Species: Homo sapiens
• Alignment Length: 995
• Identity: 172/995 - (17%)
• Similarity: 340/995 - (34%)
• Gaps: 337/995 - (33%)

  Fly    75 PKTLVLSSGATLNMFTLLSRKSLMGKEDLEL-----------YADLVSMKANASDLPSLHLPLPA 128
            |::|..|.|         ..:.::..|||||           |..|:..:   .|||
Human    19 PESLDSSDG---------DEEEVLACEDLELNPFDGLPYSSRYYKLLKER---EDLP-------- 63

  Fly   129 IRPPNLRFWTEAQLNFLTAFLGHSLSDEILQSLYASRVIVYNAALCWDKSVFLPLVILDDCRN-K 192
                   .|.|.          :|..:.:||:   ..|||...|.| .||..:|....:.|.: .
Human    64 -------IWKEK----------YSFMENLLQN---QIVIVSGDAKC-GKSAQVPQWCAEYCLSIH 107

  Fly   193 KSNVKIMC--IERQAILATYNSQRTANFFGEQLGETVGIQLPYFSAVSSSTFIIYSTAQYFLRSL 255
            ..:..::|  :.:|.::..  :.|.|:.....:|..||..:|:.:..::.|.:.|.|.....|.:
Human   108 YQHGGVICTQVHKQTVVQL--ALRVADEMDVNIGHEVGYVIPFENCCTNETILRYCTDDMLQREM 170

  Fly   256 TSQQF-RNISHLVVNDVHLHDPYTDILLSEIRMALSSHQNLRVVLLSQMGNPKKFTDFFGEGLQL 319
            .|..| .:...::::|:|.....||:||..::..|.:...|::::.|......|...::|   .:
Human   171 MSNPFLGSYGVIILDDIHERSIATDVLLGLLKDVLLARPELKLIINSSPHLISKLNSYYG---NV 232

  Fly   320 NMIKQPEVAP-RVSYLNELHSCIALAGIHKGPDIYKEIPEAFRANNPRNEQMDKCLQAYGELGTD 383
            .:|:.....| .|.||:|                            .:.:..:..|:...|
Human   233 PVIEVKNKHPVEVVYLSE----------------------------AQKDSFESILRLIFE---- 265

  Fly   384 AALRPFLYAVNYDLAPVNYRHSLTGKTAVHFASELNKANHLRLLLFMGADPYIVDLFQQNAISLA 448
                                        :|.:.|...     :::|:..:..|..:
Human   266 ----------------------------IHHSGEKGD-----IVVFLACEQDIEKV--------- 288

  Fly   449 AMNGNHECIDVLNSYSLHGYVVKSAKPDFVDYDLIIDIMYLLRTKPEYSPGEYSPGNILIILPTY 513
                   |..|....:|:        ||.                     ||      |:::|.|
Human   289 -------CETVYQGSNLN--------PDL---------------------GE------LVVVPLY 311

  Fly   514 YHIVKLNYMILSHCLTGSLQECSIFLLYDNMRNDYLQALVNASDETVK--------VVLATDIIE 570
                             ..::||:|               ...|||.|        |||.|...|
Human   312 -----------------PKEKCSLF---------------KPLDETEKRCQVYQRRVVLTTSSGE 344

  Fly   571 SLCLKVPFKYQIDTACRLNNVYDTTSCSGDDRFEWVAK-DALLRRELILQPNKGDVQCFRLISKE 634
            .|......::.||.......||:....:.....:.::: .|.:|::::...:.|...|  |.::|
Human   345 FLIWSNSVRFVIDVGVERRKVYNPRIRANSLVMQPISQSQAEIRKQILGSSSSGKFFC--LYTEE 407

  Fly   635 -AYEELSETSQPSLQTMQLDKICLAVKLLSPNTIISEYLGI----TISPPPLINVHHAVQFLKKI 694
             |.::::......:|...|..:.|.:|.:       :..|:    .::.|...::..|::.|..:
Human   408 FASKDMTPLKPAEMQEANLTSMVLFMKRI-------DIAGLGHCDFMNRPAPESLMQALEDLDYL 465

  Fly   695 DVLDDAEDVTWLGCRLMDIPVSCQLGRMLIFGILLRCLDPILTIVSSLSTAD-----PLGIPFTE 754
            ..||:..:::..|..:.:.|:..||.:.::......|:|.:|||.:.::..:     |.|.  .|
Human   466 AALDNDGNLSEFGIIMSEFPLDPQLSKSILASCEFDCVDEVLTIAAMVTAPNCFSHVPHGA--EE 528

  Fly   755 DIDNLWDRFTIYIQNSIKKERTYLSDNQFSDHFIFVRLYKEWQNRMHNRTPPLYLKDEY--EFML 817
            .....|              :|:|...  .|||..:.:||.:|:...|.:.. |..:::  ::.|
Human   529 AALTCW--------------KTFLHPE--GDHFTLISIYKAYQDTTLNSSSE-YCVEKWCRDYFL 576

  Fly   818 N-GLMEQLTSIRSEIVSSLRAANLIHSRGKLSM--NNLNQMSCNWHMVKAALTGGMYPNIYA-VD 878
            | ..:.....||:|::..::...|.::......  |.||        :|.||..|.:..|.. ||
Human   577 NCSALRMADVIRAELLEIIKRIELPYAEPAFGSKENTLN--------IKKALLSGYFMQIARDVD 633

  Fly   879 TRKSSLKSAFSGNVSMHPNTVLRDFLEPLNISAQSFRTP-WIVCNRQKSHIVYATLVVPLAVAMF 942
            .         |||..|..:..:.. |.||:..:.:.:.| |::.::
Human   634 G---------SGNYLMLTHKQVAQ-LHPLSGYSITKKMPEWVLFHK------------------- 669

  Fly   943 SGHPRIRLSPICDSEMSLTDRNVNVFIDEWIWMVMSKATAEMVMR--TRYYFFKM----YHDLLK 1001
                           .|:::.|   :|     .:.|:.:.|:.|:  .:|||..:    ..|:|:
Human   670 ---------------FSISENN---YI-----RITSEISPELFMQLVPQYYFSNLPPSESKDILQ 711

  Fly  1002 ----HCSELDMWRRD---CE 1014
                |.|.:....::   ||
Human   712 QVVDHLSPVSTMNKEQQMCE 731

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bgcn	NP_523832.2	ANK repeat	406..438	CDD:293786	4/31 (13%)
		ANK	407..>460	CDD:238125	5/52 (10%)
		Ank_2	413..>460	CDD:289560	5/46 (11%)
		HrpA	<484..973	CDD:224557	90/514 (18%)
		HA2	694..763	CDD:214852	15/73 (21%)
		OB_NTP_bind	823..945	CDD:285018	23/125 (18%)
DHX32	NP_060650.2	Preny group binding site; CAAX box	1..743		172/995 (17%)
		HrpA	12..679	CDD:224557	160/941 (17%)
		DEAD/DEXH domain	146..403		61/409 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1643
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900