Protein Alignment bgcn and dhx57

DIOPT Version :10

• Sequence 1: NP_523832.2
• Gene: bgcn / 47873
• FlyBaseID: FBgn0004581
• Length: 1215
• Species: Drosophila melanogaster
• Sequence 2: XP_021336395.2
• Gene: dhx57 / 555250
• ZFINID: ZDB-GENE-030131-4078
• Length: 1425
• Species: Danio rerio
• Alignment Length: 1061
• Identity: 223/1061 - (21%)
• Similarity: 404/1061 - (38%)
• Gaps: 275/1061 - (25%)

  Fly    35 EHEAFANNARSLGLRSQVV---HVNGNSCVKVYKQACRHYLEEPKTLVLSSGATLNMFTLLSRKS 96
            |:|::.|      ||.::|   .:......:..|:.||.:..:..                ||:
Zfish   526 ENESYVN------LRKRMVKKTEIRTEQMQEENKKLCREFKRKRS----------------SRR- 567

  Fly    97 LMGKEDLELYADLVSMKANASDLPSLHLPLPAIRPPNLRFWTEAQLNFLTAFLGHSLSDEILQSL 161
                        .:||:.....||:               |.:              .:.||:.|
Zfish   568 ------------YISMQEQRQKLPA---------------WQK--------------REAILECL 591

  Fly   162 YASRVIVYNAALCWDKSVFLPLVILDDC--RNKKSNV-KIMCIERQAILATYNSQRTANFFGEQL 223
            ..::|:|.:......|:..:|..|||:.  ..:...| .|:|.:.:.|.|...:.|.|....|.|
Zfish   592 VKNQVLVISGMTGCGKTTQIPQFILDNFLQTGRPDRVANIICTQPRRISAIAVATRVAQERAEAL 656

  Fly   224 GETVGIQLPYFSAVSSSTFIIYSTAQYFLRSLTSQ-QFRNISHLVVNDVHLHDPYTDILLSEIRM 287
            |.:.|.|:...:..||.|.:::.|....||.|... :...::|::|::||.....:|.||..::.
Zfish   657 GHSTGYQIRLETVRSSITRLMFCTTGVLLRRLEGDPELSGVTHVIVDEVHERTEESDFLLLVLKD 721

  Fly   288 ALSSHQNLRVVLLSQMGNPKKFTDFFGEGLQLNMIKQPEVAPRVSYLNELHSCIALAGIHKGPDI 352
            .:....:|:|:::|...|.:.|:.:|..            .|          ||.:.|
Zfish   722 LIVKRTDLKVIMMSATLNAELFSQYFNN------------CP----------CIHIPG------- 757

  Fly   353 YKEIP-EAFRANNPRNEQMDKCLQAYGELGTDAALRPFLYAVNYDLAPVNYRHS----------- 405
             :..| |.|...:                    |:....|.:. |.:|  ||.|
Zfish   758 -RTFPVEQFFLED--------------------AIAKTRYVIE-DGSP--YRRSTKLNRSSGPGG 798

  Fly   406 LTGKTAV-----------HFASELNKANHLRLLLFMGADPYIVDLFQQNAISLAAMNGNHECIDV 459
            .|||...           .|.|..||.:        ..|........|..:::...|.:...:..
Zfish   799 TTGKGRALVEDFDDDGGWSFTSFRNKES--------VKDSVPDQQLSQQDLTVRYSNYSKSVVKT 855

  Fly   460 LNSYSLHGYVVKSAKPDFVDYDLIIDIMYLLRTKPEYSPGEYSPGNILIILPTYYHIVKLNYMIL 524
            |.:..|          |.::.||:..::..: ...::|   |.||.:|:.||....|.:|...:.
Zfish   856 LAAMDL----------DKINMDLVESLLEWI-VDGDHS---YPPGAVLVFLPGLAEIKQLYEQLQ 906

  Fly   525 SHCLTGS--LQECSIFLLYDNMRNDYLQALVNASDETV-KVVLATDIIESLCLKVPFKYQIDTAC 586
            |:.:..:  ...|.::.|:.::.|:..||:.......| |::::|:|.|:........|.||:..
Zfish   907 SNRMFNNRRTNRCVVYPLHSSLSNEEQQAVFTRPQNGVTKIIISTNIAETSVTIDDVVYVIDSGR 971

  Fly   587 RLNNVYDTTSCSGDDRFEWVAKDALLRRELILQPNKGDVQ---CFRLISKEAYE-ELSETSQPSL 647
            .....||.:.........||::...|:|    :...|.|.   ||.|.:...:| .||:...|.:
Zfish   972 MKEKRYDASRSMESLEDVWVSRANALQR----KGRAGRVASGVCFHLFTSHRFEHHLSQQQLPEI 1032

  Fly   648 QTMQLDKICLAVKLLSP------NTIISEYLGITISPPPLINVHHAVQFLKKIDVLDDAEDVTWL 706
            |.:.|:::||.||:|..      :::.|:    .|.||...::..|.|.|..:..|.|.|.:|.|
Zfish  1033 QRVPLEQLCLRVKVLEVFAERPLDSVFSQ----LIEPPTEGSLEAAKQRLCALGALTDEESLTPL 1093

  Fly   707 GCRLMDIPVSCQLGRMLIFGILLRCLDPILTIVSSLSTADPLGIPFTEDIDNLWDRFTIYIQNSI 771
            |..|..:||..::|::::.|.:.|||||.|||.:||:...|...|        ||:    .:.:.
Zfish  1094 GWHLACLPVDVRIGKLMLLGAIFRCLDPALTIAASLAFKSPFVSP--------WDK----REEAN 1146

  Fly   772 KKERTYLSDNQFSDHFIFVRLYKEWQNRMHN--RTPPLYLKDEYEFMLNGLME------QLTSIR 828
            :|:..:...|  |||...::.||.|.|...:  :....|.::.: ..:.||.|      |...:.
Zfish  1147 EKKLAFSLAN--SDHLALMQAYKGWCNAAQSGFKAGYQYCRENF-LSIRGLQEIACLKRQFAELL 1208

  Fly   829 SEI--------------VSSLRAANLIHSRGKLSMNNLNQMSCNWHMVKAALTGGMYPNIYAVDT 879
            |:|              :||..:..::.:.|..:  |||  |.|..::.|.|...:|||:..|.:
Zfish  1209 SDIGFVKDGLKARVIEKMSSKGSDGVLEATGYEA--NLN--SDNTKLMSAMLCAALYPNVVQVRS 1269

  Fly   880 RKSSLKSAFSGNVSMHPNTVLRDFL-----------EPLNISAQSFRTPWIVCNRQ-KSHIVY-- 930
            .:...|....|.:.|.|....:.|:           ..:|.|.:.:.:|::|.:.: |:..|:
Zfish  1270 PQMKYKLTSKGAMKMQPKAEEQRFMTKSDGAVHIHPSSVNFSVRHYDSPYLVYHEKVKTSRVFIR 1334

  Fly   931 -ATLVVPLAVAMFSGHPRIRLSPICDSEMSLTDRNVNV------FI----DEWI-WMVMSKATAE 983
             .::|....:.:|.|                  ..|||      ||    |.|| :...|...||
Zfish  1335 DCSMVCVYPMVLFGG------------------GQVNVELQRGQFIISLDDGWIKFAAASHEVAE 1381

  Fly   984 MVMRTRYYFFKMYHDLLKHCS 1004
            :|...|:...::..:.:|:.|
Zfish  1382 LVKELRWELDQLLEEKIKNPS 1402

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bgcn	NP_523832.2	DEAD-like_helicase_N	155..314	CDD:475120	41/162 (25%)
		ANKYR	<398..>460	CDD:440430	14/83 (17%)
		ANK repeat	406..438	CDD:293786	8/42 (19%)
		P-loop containing Nucleoside Triphosphate Hydrolases	465..>594	CDD:476819	28/131 (21%)
		HA2	687..789	CDD:461295	33/101 (33%)
		OB_NTP_bind	862..945	CDD:400182	19/97 (20%)
dhx57	XP_021336395.2	None