Protein Alignment bgcn and Dhx57

DIOPT Version :10

• Sequence 1: NP_523832.2
• Gene: bgcn / 47873
• FlyBaseID: FBgn0004581
• Length: 1215
• Species: Drosophila melanogaster
• Sequence 2: NP_001178836.1
• Gene: Dhx57 / 366532
• RGDID: 1310340
• Length: 1391
• Species: Rattus norvegicus
• Alignment Length: 926
• Identity: 204/926 - (22%)
• Similarity: 374/926 - (40%)
• Gaps: 188/926 - (20%)

  Fly   155 DEILQSLYASRVIVYNAALCWDKSVFLPLVILDDCRN--KKSNVKIMCIERQAILATYNSQRTAN 217
            :.||:.|...:|:|.:......|:..:|..|||:..|  .:....|:|.:.:.|.|...::|.|.
  Rat   555 ETILKLLSKHQVVVISGMTGCGKTTQIPQFILDNSLNGPPERVANIICTQPRRISAISVAERVAK 619

  Fly   218 FFGEQLGETVGIQLPYFSAVSSSTFIIYSTAQYFLRSLTSQ-QFRNISHLVVNDVHLHDPYTDIL 281
            ...|::|.|||.|:...|..||:|.::|.|....||.|... ..:.::|::|::||.....:|.|
  Rat   620 ERAERVGLTVGYQIRLESVKSSATRLLYCTTGVLLRRLEGDATLQGVTHIIVDEVHERTEESDFL 684

  Fly   282 LSEIRMALSSHQNLRVVLLSQMGNPKKFTDFFGEGLQLNMIKQPEVAPRVSYLNELHSCIALAGI 346
            |..::..:.....|:|:|:|...:...|:.:|                  ||      |..:.
  Rat   685 LLVLKDIVMQRATLQVILMSATLDAGLFSKYF------------------SY------CPVIT-- 723

  Fly   347 HKGPDIYKEIP-EAFRANNPRNEQMDKCLQAYGELGTDAALRPFLYAVNYDLAPVNYRHSLTGKT 410
                     || .||..:               :...:.||....|.:. |.:|  |..|:.
  Rat   724 ---------IPGRAFPVD---------------QFFLEDALAVTRYVLQ-DGSP--YMRSMK--- 758

  Fly   411 AVHFASELNKANH-----------LRLLLFM-GADPYIVDLFQQNAISLAAMNGNHECI--DVLN 461
              ..|.|..||.|           |||.|.: ..:..:.|......:....:...::.:  .|:.
  Rat   759 --QIAKERLKARHNRTALEEVEEDLRLALHLQDEEESVKDTIPDQQLDFKQLLVRYKGVSKSVIK 821

  Fly   462 SYSLHGYVVKSAKPDFVDYDLIIDIM-YLLRTKPEYSPGEYSPGNILIILPTYYHIVKLNYMILS 525
            :.|:..:       :.|:.:||..:: :::..|..|.||.     ||:.||....|..|...:.|
  Rat   822 TMSVMDF-------EKVNLELIEALLEWIVDGKHSYPPGA-----ILVFLPGLAEIKMLYEQLQS 874

  Fly   526 HCLTGSLQ--ECSIFLLYDNMRNDYLQAL-VNASDETVKVVLATDIIESLCLKVPFKYQIDTACR 587
            :.|..:.:  .|.|..|:.::.::..||: |.......|::::|:|.|:........|.||:...
  Rat   875 NSLFNNRRSHRCVIHPLHSSLSSEEQQAVFVKPPLGVTKIIISTNIAETSITIDDVVYVIDSGKM 939

  Fly   588 LNNVYDTTSCSGDDRFEWVAKDALLRRELILQPNKGDV------QCFRLISKEAY-EELSETSQP 645
            ....||  :..|.:..|    |..:.:...|| .||..      .||.|.:...| .:|.:...|
  Rat   940 KEKRYD--AGKGMESLE----DTFVSQANALQ-RKGRAGRVASGVCFHLFTSHHYNHQLLKQQLP 997

  Fly   646 SLQTMQLDKICLAVKLL---SPNTIISEYLGITISPPPLINVHHAVQFLKKIDVLDDAEDVTWLG 707
            .:|.:.|:::||.:|:|   |.:.:.|.:..: |.||.:.::..:...|:.:..|...|.:|.||
  Rat   998 EIQRVPLEQLCLRIKILEMFSTHNLQSVFSRL-IEPPHVDSLRASKVRLRDLGALTPDEKLTPLG 1061

  Fly   708 CRLMDIPVSCQLGRMLIFGILLRCLDPILTIVSSLSTADPLGIPFTEDIDNLWDRFTIYIQNSIK 772
            ..|..:||..::|::::.|.:.|||||.|||.:||:...|...|        ||          |
  Rat  1062 YHLASLPVDVRIGKLMLLGSIFRCLDPALTIAASLAFKSPFVSP--------WD----------K 1108

  Fly   773 KERTYLSDNQF----SDHFIFVRLYKEWQNRMHNRTPPLYLKDEYEFMLNGLMEQLTSIR---SE 830
            ||.......:|    ||:...:..||.||..........|......|:....::::.|::   :|
  Rat  1109 KEEANQKKLEFAFANSDYLALLCAYKGWQLSTKESARASYNYCRQNFLSGRTLQEMASLKRQFTE 1173

  Fly   831 IVS-------SLRAANL----------IHSRGKLSMNNLNQMSCNWHMVKAALTGGMYPNIYAVD 878
            ::|       .|||..:          :.:.|:.:..|..    |..::.|.|...:|||:..|.
  Rat  1174 LLSDIGFVKEGLRAKEIEKRAQGGDGVLDATGEEANTNAE----NPKLISAVLCAALYPNVVQVK 1234

  Fly   879 TRKSSLKSAFSGNVSMHPNTVLRDFL-----------EPLNISAQSFRTPWIVCNRQ-KSHIVY- 930
            |.:...:...||.|.:.|.:....|:           ..:|...:.|.:|:::.:.: |:..|:
  Rat  1235 TPEGKFQKTSSGVVRLQPKSAELKFVTKNDGYVHIHPSSVNYQVRHFDSPYLLYHEKIKTSRVFI 1299

  Fly   931 --ATLVVPLAVAMFSGHPRIRLSPICDSEMSLTDRNVNVFI----DEWI-WMVMSKATAEMVMRT 988
              .::|....:.:|.|           .::|:..:. ..|:    |.|| ::..|...||:|...
  Rat  1300 RDCSMVSVYPLVLFGG-----------GQVSVQLQR-GAFVVSLDDGWIRFVAASHQVAELVKEL 1352

  Fly   989 RYYFFKMYHDLLKHCS 1004
            |....::..|.:|:.|
  Rat  1353 RCELDQLLQDKIKNPS 1368

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bgcn	NP_523832.2	DEAD-like_helicase_N	155..314	CDD:475120	44/161 (27%)
		ANKYR	<398..>460	CDD:440430	13/75 (17%)
		ANK repeat	406..438	CDD:293786	9/43 (21%)
		P-loop containing Nucleoside Triphosphate Hydrolases	465..>594	CDD:476819	29/132 (22%)
		HA2	687..789	CDD:461295	31/105 (30%)
		OB_NTP_bind	862..945	CDD:400182	19/97 (20%)
Dhx57	NP_001178836.1	UBA_DHX57	184..221	CDD:270502
		RWD_DHX57	245..428	CDD:467661
		zf_CCCH_4	308..326	CDD:465719
		HrpA	548..>1175	CDD:441249	164/715 (23%)
		OB_NTP_bind	1218..1315	CDD:400182	19/96 (20%)