Protein Alignment bgcn and Dhx35

DIOPT Version :10

• Sequence 1: NP_523832.2
• Gene: bgcn / 47873
• FlyBaseID: FBgn0004581
• Length: 1215
• Species: Drosophila melanogaster
• Sequence 2: NP_001402786.1
• Gene: Dhx35 / 362260
• RGDID: 1311165
• Length: 703
• Species: Rattus norvegicus
• Alignment Length: 737
• Identity: 136/737 - (18%)
• Similarity: 267/737 - (36%)
• Gaps: 205/737 - (27%)

  Fly   273 LHDPYTDILLSEIR-----MALSSH-----QNLR-VVLLSQMGNPKKF--------TDFFGEGLQ 318
            :::||..:.:.:.|     ..|.:|     :|.: ||::.:.|..|..        ..:..||..
  Rat    38 IYNPYAALSIEQQRQKLPVFKLRNHILYLVENYQTVVIVGETGCGKSTQVPQYLAEAGWTAEGRV 102

  Fly   319 LNMIKQPEVAPRVSYLNELHSCIALAG---IHKGPDIYKEIPEAFRANNPRNEQMDKCLQAY--- 377
            :.:.:...||           .:.:||   ..:|..:..|:....|        .|.|....
  Rat   103 VGVTQPRRVA-----------AVTVAGRVADERGAVLGHEVGYCIR--------FDDCTDPLATR 148

  Fly   378 ------GELGTDAALRPFLYAVNYDLAPVNYRHSLTGKT--AVHFASEL-NKANHLRLLL---FM 430
                  |.|..:..:.|.|  ..|.:..::..|..|..|  |:....:: .|...|||::   .:
  Rat   149 IKFLTDGMLVREMMVDPLL--TKYSVVMLDEAHERTLYTDIAIGLLKKIQKKRGDLRLIVASATL 211

  Fly   431 GADPYIVDLFQQNAIS--------LAAMNGNHECIDVLNSYSLHGYVVKSAKPDFV--DYDLIID 485
            .|:.: .|.|.||..|        :..:.|....:|:        :.::|..||::  ..|.::.
  Rat   212 DAEKF-RDFFNQNETSDPARDTCVILTVEGRTFPVDI--------FYLQSPVPDYIKATVDTVVK 267

  Fly   486 IMYLLRTKPEYSPGEYSPGNILIILPTYYHIVKLNYMILSH----CLTGSLQECSIFLLYDNMRN 546
            |        ..:.|:   |:||..|.....:..:..|::..    ..||..:...:..:|..:.:
  Rat   268 I--------HQTEGD---GDILAFLTGQEEVETVVSMLIEQARALARTGMKKHLRVLPMYAGLPS 321

  Fly   547 -DYLQALVNASDETVKVVLATDIIESLCLKVPFKYQID------------TACRLNNVYDTTSCS 598
             :.::.....|....||::||::.|:........|.||            ||.....|...:..|
  Rat   322 FEQMKVFERVSHSVRKVIVATNVAETSITISGIVYVIDCGFMKLRAYNPRTAIECLVVVPVSQAS 386

  Fly   599 GDDRFEWVAKDALLRRELILQPNKG----DVQCFRLISKEAYEELSETSQPSLQTMQLDKICLAV 659
            .:.|                 ..:|    ..:|:||.::||:|:|.:::.|.:|...|..:.|.:
  Rat   387 ANQR-----------------AGRGGRNRSGKCYRLYTEEAFEQLPQSTVPEMQRSNLAPVVLQL 434

  Fly   660 KLLSPNTIISEYLGITISPPPLINVHHAVQFLKKIDVLD-DAEDVTWLGCRLMDIPVSCQLGRML 723
            |.|..::::..:.   :||||..::..|::.|..:..|| |......||.|:.:.|::....:||
  Rat   435 KALGIDSVLRFHF---MSPPPAQSMVQALELLYALGGLDKDCRLTEPLGMRIAEFPLNPMFAKML 496

  Fly   724 I----FGILLRCLDPILTIVSSLSTADPLGIPFTEDIDNLWDRFTIYIQNSIKKERTYLSDNQFS 784
            :    ||    |...||:|.:.:            .|.|      :::..|.:|.:......:|:
  Rat   497 LESGNFG----CSQEILSIAAMM------------QIQN------VFVFPSNQKSQATRVHRKFA 539

  Fly   785 ----DHFIFVRLYKEWQNRMHNRTPPLYLKDEYEFMLN--GLMEQLTSIRSEIVSSLRAANLIHS 843
                ||...:.:|:.:..  ||::....    .|..||  ||              :|||.:
  Rat   540 VEEGDHLTMLNVYEAFIK--HNKSSQWC----QEHFLNYKGL--------------VRAATV--- 581

  Fly   844 RGKLSMNNLNQMSCNWHMVKAALTGGMYPNIYAVDTRKSSLKSAFSGNVSMHPNT----VLRD-- 902
                 .:.|.::...:.:.|.:..|...|.:..:       .|.|..|.:...:|    .:||
  Rat   582 -----RDQLKKLLVKFQVPKMSSEGDPDPVLRCI-------VSGFFANAARFHSTGAYRTIRDDH 634

  Fly   903 --FLEPLNISAQSFRTPWIVCN 922
              .:.|.::........|::.|
  Rat   635 ELHIHPASVLYAEKPPRWVIYN 656

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bgcn	NP_523832.2	DEAD-like_helicase_N	155..314	CDD:475120	10/59 (17%)
		ANKYR	<398..>460	CDD:440430	16/75 (21%)
		ANK repeat	406..438	CDD:293786	8/37 (22%)
		P-loop containing Nucleoside Triphosphate Hydrolases	465..>594	CDD:476819	26/147 (18%)
		HA2	687..789	CDD:461295	24/110 (22%)
		OB_NTP_bind	862..945	CDD:400182	12/69 (17%)
Dhx35	NP_001402786.1	HrpA	54..>701	CDD:441249	133/721 (18%)