Protein Alignment bgcn and Dhx37

DIOPT Version :10

• Sequence 1: NP_523832.2
• Gene: bgcn / 47873
• FlyBaseID: FBgn0004581
• Length: 1215
• Species: Drosophila melanogaster
• Sequence 2: XP_017176254.1
• Gene: Dhx37 / 208144
• MGIID: 3028576
• Length: 1161
• Species: Mus musculus
• Alignment Length: 865
• Identity: 155/865 - (17%)
• Similarity: 308/865 - (35%)
• Gaps: 222/865 - (25%)

  Fly   126 LPAIRPPNLRFWTEAQLNFLTAFLGHSLSDE--ILQSLYASRVIVYNAALCWDKSVFLPLVILDD 188
            :|..|.|.::   |.:|..      ..|::|  |::::....:::........|:..:|..:.:.
Mouse   233 IPVNRTPEMQ---EERLKL------PILAEEQAIMEAVAEHPIVIVCGETGSGKTTQVPQFLYEA 288

  Fly   189 CRNKKSNVKIMCIERQAILATYNSQRTANFFGEQLG---ETVGIQLPYFSAVSSSTFIIYSTAQY 250
            ..:.:.:: |...|.:.:.|...|||.|    :::.   ..|..|:.|...|:..|.|.:.|...
Mouse   289 GYSSEDSI-IGVTEPRRVAAVAMSQRVA----KEMNLSHRVVSYQIRYEGNVTEETRIKFMTDGV 348

  Fly   251 FLRSLTSQQFRNISH--LVVNDVHLHDPYTDILLS----EIRMALSSHQNLRVVLLSQMGNPKKF 309
            .|:.: .:.|..:.:  :::::.|....||||||.    .:.:....|..|:::::|.....:.|
Mouse   349 LLKEI-QKDFLLLKYKVVIIDEAHERSVYTDILLGLLSRIVALRAKRHLPLKLLIMSATLRVEDF 412

  Fly   310 TDFFGEGLQLNMIKQPEVAPRVSYLNELHSCIALAGIHKGPDIYKEIPEA--FRANNPRNEQMDK 372
            |.      ...:...|....:|.                    .::.|..  |....|.::...:
Mouse   413 TQ------NQRLFTTPPPVIKVE--------------------SRQFPVTVHFNKRTPLDDYSGE 451

  Fly   373 CLQAYGELGTDAALRPFLYAVNYDLAPV-NYRHSLTGKTAVH-FASELNKANHLRLLLFMGADPY 435
            |.:...::              :.:.|. .....|||:..|| ....|.||     ..|..:.|.
Mouse   452 CFRKVCKI--------------HRMLPAGGILVFLTGQAEVHALCRRLRKA-----FPFRCSQPQ 497

  Fly   436 IVD--------LFQQN--------AISLAAMNGNHECIDVLNSYSL----HGYVVKSAKPD---- 476
            ..:        .|:::        |::|..:|        |::||:    .|...:.|:.|
Mouse   498 EKEEDSAEGMRRFKKSRTRARKAQAMALPQIN--------LDNYSVLPAGEGDEDREAEMDDEEE 554

  Fly   477 FVDYDLIIDIMYLLRTKPEYSPGEYSPGNI-LIILPTYYHIVKLNYMILSHCLTGSLQECSIFLL 540
            .:..||.:|:     ...|.:.||....:: |.:||.|             .|....::..:|
Mouse   555 ALGSDLDLDL-----GDSEANEGEQPDASLPLHVLPLY-------------SLLAPEKQAQVF-- 599

  Fly   541 YDNMRNDYLQALVNASDETVKVVLATDIIESLCLKVP-FKYQIDTACRLNNVYDTTSCSGDDRFE 604
                        ....:.|...|:||::.|: .|.:| .||.:|........||..:.....|..
Mouse   600 ------------KPPPEGTRLCVVATNVAET-SLTIPGIKYVVDCGKVKKRYYDRVTGVSSFRVT 651

  Fly   605 WVAK---DALLRRELILQPNKGDVQCFRLISKEAYEELSETSQPSLQTMQLDKICLAVKLLSPNT 666
            ||::   |....|....:|.    .|:||.|...:.:..:...|.:....::.:.|.:|.||
Mouse   652 WVSQASADQRAGRAGRTEPG----HCYRLYSSAVFGDFEQFPPPEITRRPVEDLILQMKALS--- 709

  Fly   667 IISEYLGITISPPPLINVHHAVQFL----------------KKIDVLDDAEDVTWLGCRLMDIPV 715
             |.:.:......||.:....|.:.|                ||:.:...:..:|.||..:...||
Mouse   710 -IEKVINFPFPTPPSVEALVAAEELLVALGALQAPPKQERMKKLQMSQLSCPITALGRTMSTFPV 773

  Fly   716 SCQLGRMLIFGILLRCLDPILTIVSSLSTADPLGIPFTEDIDNLWDRFTIYIQNSIKKERTYLSD 780
            :.:..:||.......||...:.||::::..:     ..|::|.         ..:.:||...|..
Mouse   774 APRYAKMLALSQQHGCLPYTIAIVAAMTVRE-----LFEELDR---------PAASEKELAELKG 824

  Fly   781 NQFSDHFIFVRLYKEWQNRMHNRTPPLYLKD-----------EY-----EF-MLNGL----MEQL 824
            .:..    ..::.:.|.    .:.|.|.|.|           ||     :| ..|||    |.::
Mouse   825 RRAR----VAQMKRTWA----GQGPSLKLGDLMVLLGAVGACEYAGCSPQFCQANGLRYKAMLEI 881

  Fly   825 TSIRSEIVSSLRA----ANLIHSRGKLSMNNLNQMSCNWHMVKAALTGGMYPNIYAVDTRKSSLK 885
            ..:|.::.:::.|    |.|... .|:.....:|::....::.|.|...:...:.:.|......|
Mouse   882 RRLRGQLTTAVNAVCPEAGLFLD-PKMQPPTESQVTYLRQIMAAGLGDHLARRVQSEDLLDPKWK 945

  Fly   886 SAF-----SGNVSMHPNTVL 900
            :|:     ...|.:||::||
Mouse   946 NAYKTPLLDDPVFIHPSSVL 965

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bgcn	NP_523832.2	DEAD-like_helicase_N	155..314	CDD:475120	32/169 (19%)
		ANKYR	<398..>460	CDD:440430	15/79 (19%)
		ANK repeat	406..438	CDD:293786	10/32 (31%)
		P-loop containing Nucleoside Triphosphate Hydrolases	465..>594	CDD:476819	26/138 (19%)
		HA2	687..789	CDD:461295	20/117 (17%)
		OB_NTP_bind	862..945	CDD:400182	10/44 (23%)
Dhx37	XP_017176254.1	HrpA	248..>1036	CDD:441249	150/847 (18%)